Search International and National Patent Collections

1. (WO2001038397) N-ALKYLATED PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY

Pub. No.:    WO/2001/038397    International Application No.:    PCT/US2000/032105
Publication Date: Fri Jun 01 01:59:59 CEST 2001 International Filing Date: Thu Nov 23 00:59:59 CET 2000
IPC: A61K 38/00
C07K 7/08
C07K 14/78
Applicants: ABBOTT LABORATORIES
Inventors: HAVIV, Fortuna
HENKIN, Jack
BRADLEY, Michael, F.
KALVIN, Douglas, M.
Title: N-ALKYLATED PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY
Abstract:
N-Alkylated peptides of the formula (I) Xaa1- Xaa2- Xaa3- Xaa4- Xaa5- Xaa6- Xaa7- Xaa8- Xaa9- Xaa10- Xaa11-, are useful for inhibiting angiogenesis. Also disclosed are angiogenesis-inhibiting compositions and methods of inhibiting angiogenesis in a mammal.