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1. (WO2001038381) A NOVEL POLYPEPTIDE - HUMAN cGMP-INHIBITED PHOSPHODIESTERASE 17 AND A POLYNUCLEOTIDE ENCODING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/038381 International Application No.: PCT/CN2000/000451
Publication Date: 31.05.2001 International Filing Date: 20.11.2000
Chapter 2 Demand Filed: 20.06.2001
IPC:
A61K 38/00 (2006.01) ,C12N 9/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14
Hydrolases (3.)
16
acting on ester bonds (3.1)
Applicants: MAO, Yumin[CN/CN]; CN (UsOnly)
XIE, Yi[CN/CN]; CN (UsOnly)
BIOROAD GENE DEVELOPMENT LTD. SHANGHAI[CN/CN]; 12F, 3rd Building No. 1111 Zhongshan Bei Er Rd Shanghai 200092, CN (AllExceptUS)
Inventors: MAO, Yumin; CN
XIE, Yi; CN
Agent: WATSON & BAND LAW OFFICES; 11th Floor 61 Nanjing Rd (E) Shanghai 200002, CN
Priority Data:
99124077.423.11.1999CN
Title (EN) A NOVEL POLYPEPTIDE - HUMAN cGMP-INHIBITED PHOSPHODIESTERASE 17 AND A POLYNUCLEOTIDE ENCODING THE SAME
(FR) NOUVEAU POLYPEPTIDE PHOSPHODIESTERASE 17 HUMAINE INHIBEE PAR GMPC ET POLYNUCLEOTIDE LE CODANT
Abstract:
(EN) The present invention discloses a novel polypeptide - human cGMP-inhibited phosphodiesterase 17 and a polynucleotide encoding the same, as well as a method of producing the polypeptide by DNA recombinant technology. The present invention also discloses methods of using the polypeptide in treatment of various disease, such as malignant tumor, blood disease, HIV infection, immunological disease and various inflammation. The present invention also discloses an antagonist against the polypeptide and the therapeutic use of the same. The present invention also discloses the use of such polynucleotide encoding human cGMP-inhibited phosphodiesterase 17.
(FR) La présente invention concerne un nouveau polypeptide phosphodiestérase 17 humaine inhibée par GMPc ainsi qu'un polynucléotide le codant, de même qu'une méthode de production du polypeptide par génie génétique. La présente invention concerne également des méthodes d'utilisation du polypeptide dans le traitement de diverses maladies, telles que des tumeurs malignes, des maladies du sang, des infections à VIH, des maladies immunologiques et diverses inflammations. La présente invention concerne également un antagoniste contre le polypeptide et l'utilisation thérapeutique de celui-ci. En outre, la présente invention concerne l'utilisation de ce polynucléotide codant la phosphodiestérase 17 humaine inhibée par GMPc.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)