Search International and National Patent Collections

1. (WO2001038325) 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY

Pub. No.:    WO/2001/038325    International Application No.:    PCT/JP2000/007877
Publication Date: Fri Jun 01 01:59:59 CEST 2001 International Filing Date: Fri Nov 10 00:59:59 CET 2000
IPC: C07D 231/12
C07D 401/12
C07D 401/14
C07D 405/12
C07D 409/12
C07D 409/14
C07D 413/12
C07D 417/14
Applicants: TAKEDA CHEMICAL INDUSTRIES, LTD.
MOMOSE, Yu
MAEKAWA, Tsuyoshi
ODAKA, Hiroyuki
KIMURA, Hiroyuki
Inventors: MOMOSE, Yu
MAEKAWA, Tsuyoshi
ODAKA, Hiroyuki
KIMURA, Hiroyuki
Title: 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY
Abstract:
A compound of formula (I) F wherein R1 represents a hydrocarbon group which may be substituted or a heterocyclic group which may be substituted; x represents a bond, an oxygen atom, a sulfur atom, or a group of the formula: -CO-, -CS-, -CR4(OR5)- or -NR6- wherein each of R?4 and R6¿ represents a hydrogen atom or a hydrocarbon group which may be stubstituted, R5 represents a hydrogen atom or a protective group for a hydroxyl group; m represents an integer of 0 to 3; Y represents an oxygen atom, a sulfur atom, or a group of the formula: -SO-, -SO¿2?-, -NR7-, -CONR7- or -NR?7¿CO- wherein R7 represents a hydrogen atom or a hydrocarbon group which may be substituted; ring A represents an aromatic ring which may further have 1 to 3 substituents; n represents an integer of 1 to 8; ring B represents a nitrogen-containing 5-membered hetero ring which may further be substituted by an alkyl group.