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1. (WO2001038268) APPARATUS AND METHOD FOR SYNTHESIZING COMBINATORIAL LIBRARIES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/038268 International Application No.: PCT/US2000/032104
Publication Date: 31.05.2001 International Filing Date: 22.11.2000
Chapter 2 Demand Filed: 14.06.2001
IPC:
B01J 19/00 (2006.01)
Applicants: SELECTIDE CORPORATION[US/US]; 1580 East Hanley Boulevard Tucson, AZ 85737, US
Inventors: PATEK, Marcel; US
PAVEL, Safar; US
SMRCINA, Martin; US
WEGRZYNIAK, Eric; US
STROP, Peter; US
FLYNN, Gary, A.; US
BAUM, Stephen, A.; US
Agent: BALDWIN, Geraldine, F. ; Pennie & Edmonds LLP 1155 avenue of the Americas New York, NY 10036, US
Priority Data:
09/449,22224.11.1999US
Title (EN) APPARATUS AND METHOD FOR SYNTHESIZING COMBINATORIAL LIBRARIES
(FR) APPAREIL ET PROCEDE PERMETTANT DE SYNTHETISER DES BIBLIOTHEQUES COMBINATOIRES
Abstract:
(EN) An apparatus and method for synthesizing a combinatorial library comprising a plurality of chemical compounds such that the chemical composition of each compound is easily tracked. The library compounds are synthesized on solid-phase supports, which are spatially arranged in frames during synthesis according to a predetermined protocol, such that each solid-phase support passes through a series of unique spatial 2D or 3D addresses by which the chemical composition of each compound may be determined at any point during synthesis. Solid-phase supports include hollow tubular-lanterns and gears.
(FR) L'invention concerne un appareil et un procédé permettant de synthétiser une bibliothèque combinatoire comprenant plusieurs composés chimiques, de telle manière que la composition chimique de chaque composé est facilement suivie. Les composés de la bibliothèque sont synthétisés sur des supports à phase solide, qui sont spatialement disposés dans des cadres pendant la synthèse selon un protocole prédéterminé, de telle manière que chaque support à phase solide passe à travers une série d'adresses spatiales uniques en 2D ou 3D, par le biais desquelles la composition chimique de chaque composé peut être déterminée à n'importe quel stade de la synthèse. Des supports à phase comprennent des lanternes tubulaires creuses et des engrenages.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)