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Machine translation
1. (WO2001037855) TEMPERATURE DEPENDENT NEURONAL RESCUE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/037855    International Application No.:    PCT/US2000/041591
Publication Date: 31.05.2001 International Filing Date: 26.10.2000
Chapter 2 Demand Filed:    25.05.2001    
IPC:
A61K 38/18 (2006.01), A61K 38/30 (2006.01)
Applicants: CHIRON CORPORATION [US/US]; 4560 Horton Street, Emeryville, CA 94608-2916 (US) (For All Designated States Except US).
GLUCKMAN, Peter, David [NZ/NZ]; (NZ) (For US Only).
GUAN, Jian [NZ/NZ]; (NZ) (For US Only).
GUNN, Alistair, Jan [NZ/NZ]; (NZ) (For US Only)
Inventors: GLUCKMAN, Peter, David; (NZ).
GUAN, Jian; (NZ).
GUNN, Alistair, Jan; (NZ)
Agent: GUTH, Joseph, H.; Chiron Corporation, Intellectual Property - R338, P.O. Box 8097, Emeryville, CA 94622-8097 (US)
Priority Data:
60/161,798 27.10.1999 US
Title (EN) TEMPERATURE DEPENDENT NEURONAL RESCUE
(FR) SAUVETAGE NEURONAL FONCTION DE LA TEMPERATURE
Abstract: front page image
(EN)Methods are provided for the treatment and/or prevention of neuronal damage following a CNS insult. Specifically, the methods comprise modulating the cerebral cortex temperature during the recovery phase of a CNS insult and the administration of a neurologic therapeutic agent. The modulation in cerebral temperature is such as to extend the period of time following the CNS insult during which the neurologic therapeutic agent is capable of eliciting a neuroprotective effect.
(FR)L'invention concerne des procédés destinés au traitement et/ou à la prévention de blessure neuronale à la suite d'une agression sur le système nerveux central. Les procédés consistent, spécifiquement, à moduler la température du cortex cérébral lors de la phase de récupération suivant une agression du système nerveux central, et à administrer un agent thérapeutique neurologique. La modulation de la température cérébrale est telle que sa durée s'étend pendant la période de temps, suivant l'agression du système nerveux central, durant laquelle l'agent thérapeutique neurologique est capable de provoquer un effet neuroprotecteur.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)