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Machine translation
1. (WO2001037834) STABLE ACID LABILE BENZIMIDAZOLE PHARMACEUTICAL COMPOSITIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/037834    International Application No.:    PCT/IB2000/001842
Publication Date: 31.05.2001 International Filing Date: 22.11.2000
Chapter 2 Demand Filed:    04.06.2001    
IPC:
A61K 9/48 (2006.01), A61K 31/355 (2006.01), A61K 31/4439 (2006.01), A61K 47/22 (2006.01)
Applicants: DEBOECK, Arthur, M. [BE/US]; (US) (For US Only).
VAN DER BIEST, Francis [BE/BE]; (BE) (For US Only).
BAUDIER, Philippe, R. [FR/BE]; (BE) (For US Only).
GALEPHAR PHARMACEUTICAL RESEARCH, INC. [US/US]; Road 198 Km 14.7 Num.100, Juncos, Puerto Rico 00777-3873 (US) (For All Designated States Except US)
Inventors: DEBOECK, Arthur, M.; (US).
VAN DER BIEST, Francis; (BE).
BAUDIER, Philippe, R.; (BE)
Agent: BEAUMONT, William, E.; Oblon, Spivak, McClelland, Maier & Neustadt, P.C., Fourth Floor, Crystal Square Five, 1755 Jefferson Davis Highway, Arlington, VA 22202 (US)
Priority Data:
60/166,761 22.11.1999 US
Title (EN) STABLE ACID LABILE BENZIMIDAZOLE PHARMACEUTICAL COMPOSITIONS
(FR) COMPOSITIONS PHARMACEUTIQUES STABLES AU BENZIMIDAZOLE LABILE ACIDE
Abstract: front page image
(EN)The present invention relates to a novel oral pharmaceutical stable formulation containing an acid labile benzimidazole compound, which is stabilized with a vitamin E derivative. More specifically, the composition comprises the acid labile benzimidazole compound in solution and/or suspension in oil and/or oil derivatives and a vitamin E derivative as stabilizer. A particular embodiment comprising omeprazole as acid labile benzimidazole compound and vitamin E Polyethylene glycol succinate as vitamin E stabilizer derivative is disclosed.
(FR)L'invention concerne une nouvelle formulation pharmaceutique orale stable renfermant un composé benzimidazole labile acide, stabilisé au moyen d'un dérivé de vitamine E. Plus spécialement, la composition renferme le composé benzimidazole labile acide en solution et/ou en suspension dans de l'huile et/ou des dérivés d'huile, et un dérivé de vitamine E comme stabilisateur. Un mode de réalisation particulier comprend l'oméprazole comme composé benzimidazole labile acide et le succinate de polyéthylèneglycol comme dérivé du stabilisateur de vitamine E.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)