WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2001036641) DOUBLE-STRANDED RNA RECEPTOR (dsRNA-R) AND METHODS RELATING THERETO
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/036641    International Application No.:    PCT/US2000/041726
Publication Date: 25.05.2001 International Filing Date: 01.11.2000
Chapter 2 Demand Filed:    31.05.2001    
IPC:
C07K 14/705 (2006.01)
Applicants: CHIRON CORPORATION [US/US]; 4560 Horton Street, Emeryville, CA 94608 (US) (For All Designated States Except US).
MACKICHAN, Mary, Lee [US/US]; (US) (For US Only)
Inventors: MACKICHAN, Mary, Lee; (US)
Agent: HARBIN, Alisa, A.; Chiron Corporation, Intellectual Property - R440, P.O. Box 8097, Emeryville, CA 94662-8097 (US)
Priority Data:
60/163,157 02.11.1999 US
60/167,389 24.11.1999 US
Title (EN) DOUBLE-STRANDED RNA RECEPTOR (dsRNA-R) AND METHODS RELATING THERETO
(FR) DETECTEURS DES RECEPTEURS D'ARN DOUBLE BRIN (dsRNA-R) ET PROCEDES CORRESPONDANTS
Abstract: front page image
(EN)The present invention is directed to nucleic acid molecules and polypeptides encoding a dsRNA receptor (dsRNA-R). The dsRNA-R contains a THD, interacts with the MyD88 adapter protein, and may bind to dsRNA. The present invention is also directed to antibodies against dsRNA-R and to methods of modulating an immune response and the methods of identifying compounds which bind to and/or modulate dsRNA-R.
(FR)L'invention concerne des molécules d'acides nucléiques et des polypeptides codant un récepteur d'ARN double brin (dsRNA-R). Le dsRNA-R contient un domaine THD, interagit avec la protéine d'adaptation MyD88 et peut se lier au dsRNA. La présente invention concerne aussi des anticorps dirigés contre dsRNA-R, des procédés pour moduler une réponse immunitaire et des procédés d'identification des composés qui se lient à dsRNA-R et/ou le modulent.
Designated States: CA, JP, US.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR).
Publication Language: English (EN)
Filing Language: English (EN)