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Machine translation
1. (WO2001036640) HUMAN FGF-21 GENE AND GENE EXPRESSION PRODUCTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/036640    International Application No.:    PCT/US2000/031745
Publication Date: 25.05.2001 International Filing Date: 16.11.2000
Chapter 2 Demand Filed:    12.06.2001    
IPC:
C07K 14/50 (2006.01)
Applicants: CHIRON CORPORATION [US/US]; 4560 Horton Street, Emeryville, CA 94608 (US).
KYOTO UNIVERSITY [JP/JP]; Yoshida-Shimoadachi, Sakyo, Kyoto 606-8501 (JP)
Inventors: ITOH, Nobuyuki; (JP).
KAVANAUGH, W., Michael; (US)
Agent: POTTER, Jane, E.; SEED Intellectual Property Law Group PLLC, Suite 6300, 701 Fifth Avenue, Seattle, WA 98104-7092 (US).
GOLDIN, Douglas, Michael; J.A. Kemp & Co., 14 South Square, Gray's Inn, London WC1R 5JJ (GB)
Priority Data:
60/166,540 18.11.1999 US
60/203,633 11.05.2000 US
Title (EN) HUMAN FGF-21 GENE AND GENE EXPRESSION PRODUCTS
(FR) GENE HUMAIN FGF-21 ET PRODUITS D'EXPRESSION GENIQUE
Abstract: front page image
(EN)This invention relates to human fibroblast growth factor (hFGF-21), and to variants thereof and to polynucleotides encoding FGF-21. The invention also relates to diagnostic and therapeutic agents related to the polynucleotides and proteins, including probes and antibodies, and to methods of treating liver disease such as cirrhosis and cancer, methods of treating conditions related to thymic function, and methods of treating conditions of the testis. The invention also relates to mouse fibroblast growth factor (mFGF-21), and to variants thereof and polynucleotides encoding mFGF-21.
(FR)L'invention concerne le facteur humain de croissance des fibroblastes (hFGF-21), ses variantes ainsi que des polynucléotides codant pour FGF-21. L'invention concerne également des agents diagnostiques et thérapeutiques associés à des polynucléotides et à des protéines, y compris des sondes et des anticorps ; des méthodes de traitement de maladies du foie telles que la cirrhose et le cancer ; des méthodes de traitement de maladies associées à la fonction thymique ; des méthodes de traitement de maladies des testicules. L'invention concerne en outre le facteur murin de croissance des fibroblastes (mFGF-21), ses variantes ainsi que des polynucléotides codant pour mFGF-21.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)