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1. (WO2001036431) DIAMINO PLATINUM (II) ANTITUMOR COMPLEXES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/036431 International Application No.: PCT/US2000/031297
Publication Date: 25.05.2001 International Filing Date: 15.11.2000
Chapter 2 Demand Filed: 05.06.2001
IPC:
C07F 15/00 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
F
ACYCLIC, CARBOCYCLIC, OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
15
Compounds containing elements of the 8th Group of the Periodic System
Applicants: UCKUN, Fatih, M.[US/US]; US (UsOnly)
NARLA, Rama, K.[IN/US]; US (UsOnly)
PARKER HUGHES INSTITUTE[US/US]; 2665 Long Lake Road St. Paul, MN 55113, US (AllExceptUS)
Inventors: UCKUN, Fatih, M.; US
NARLA, Rama, K.; US
Agent: DAIGNAULT, Ronald, A.; Merchant & Gould P.C. P.O. Box 2903 Minneapolis, MN 55402-0903, US
Priority Data:
60/165,65215.11.1999US
Title (EN) DIAMINO PLATINUM (II) ANTITUMOR COMPLEXES
(FR) COMPLEXES ANTITUMORAUX A BASE DE DIAMINO PLATINE (II)
Abstract:
(EN) The present invention describes diamino platinum (II) compounds and compositions useful for treating a subject with a tumor and/or inducing apoptosis in a population of cells. The present invention also describes pharmaceutical compositions containing the aforementioned inventive compound(s) in combination with a pharmaceutical acceptable carrier. Additionally, the invention further provides a method of inducing apoptosis in a population of cells and a method of treating a subject with a tumor, wherein the method comprises administering to the subject a therapeutically effective amount of the aforementioned compound(s) or composition(s).
(FR) La présente invention concerne des composés et des compositions à base de diamino platine (II) que l'on utilise pour traiter un sujet présentant une tumeur et/ou pour induire l'apoptose au niveau d'une population de cellules. La présente invention concerne également des compositions pharmaceutiques contenant les composés précités combinés à un excipient pharmaceutiquement acceptable. En outre, l'invention concerne une méthode permettant d'induire l'apoptose dans une population de cellules, ainsi qu'une méthode de traitement destinée à un sujet présentant une tumeur, ladite méthode consistant à administrer audit sujet une dose thérapeutiquement efficace des composés ou compositions susmentionnées.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)