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1. (WO2001036402) NOVEL 2-(N-CYANOIMINO)THIAZOLIDIN-4-ONE DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/036402 International Application No.: PCT/JP1999/006352
Publication Date: 25.05.2001 International Filing Date: 12.11.1999
IPC:
C07D 277/20 (2006.01) ,C07D 277/54 (2006.01) ,C07D 277/64 (2006.01) ,C07D 277/74 (2006.01) ,C07D 417/12 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
277
Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
02
not condensed with other rings
20
having two or three double bonds between ring members or between ring members and non-ring members
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
277
Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
02
not condensed with other rings
20
having two or three double bonds between ring members or between ring members and non-ring members
32
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
54
Nitrogen and either oxygen or sulfur atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
277
Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
60
condensed with carbocyclic rings or ring systems
62
Benzothiazoles
64
with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
277
Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
60
condensed with carbocyclic rings or ring systems
62
Benzothiazoles
68
with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
70
Sulfur atoms
74
Sulfur atoms substituted by carbon atoms
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
417
Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/196
02
containing two hetero rings
12
linked by a chain containing hetero atoms as chain links
Applicants:
YONEDA, Fumio [JP/JP]; JP (UsOnly)
OHDE, Hironori [JP/JP]; JP (UsOnly)
WATANABE, Mayumi [JP/JP]; JP (UsOnly)
ANDO, Takashi [JP/JP]; JP (UsOnly)
YASUSA, Takuya [JP/JP]; JP (UsOnly)
UEGAKI, Yuko [JP/JP]; JP (UsOnly)
FUJIMOTO BROTHERS CO., LTD. [JP/JP]; 3-40, Nishiotsuka 1-chome Matsubara-shi Osaka 580-0011, JP (AllExceptUS)
Inventors:
YONEDA, Fumio; JP
OHDE, Hironori; JP
WATANABE, Mayumi; JP
ANDO, Takashi; JP
YASUSA, Takuya; JP
UEGAKI, Yuko; JP
Common
Representative:
FUJIMOTO BROTHERS CO., LTD.; 3-40, Nishiotsuka 1-chome Matsubara-shi Osaka 580-0011, JP
Priority Data:
Title (EN) NOVEL 2-(N-CYANOIMINO)THIAZOLIDIN-4-ONE DERIVATIVES
(FR) NOUVEAUX DERIVES DE 2-(N-CYANO-IMINO)THIAZOLIDIN-4-ONE
Abstract:
(EN) Novel 2-(N-cyanoimino)thiazolidin-4-one derivatives represented by general formula (I), which exhibit excellent cholesterol-lowering and triglyceride-lowering activities and are useful in the prevention or treatment of hyperlipidemia and diseases resulting therefrom.
(FR) Cette invention se rapporte à de nouveaux dérivés de 2-(N-cyano-imino)thiazolidin-4-one, représentés par la formule générale (I), qui possèdent un excellent pouvoir d'abaissement du cholestérol et d'abaissement des triglycérides et qui sont utiles pour prévenir ou traiter l'hyperlipidémie et les maladies qui en résultent.
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Designated States: AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CU, CZ, DE, DK, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, UA, UG, US, UZ, VN, YU, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)