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Machine translation
1. (WO2001035970) VIRUSES FOR THE TREATMENT OF CELLULAR PROLIFERATIVE DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/035970    International Application No.:    PCT/CA2000/001329
Publication Date: 25.05.2001 International Filing Date: 08.11.2000
Chapter 2 Demand Filed:    25.05.2001    
IPC:
A61K 35/76 (2006.01)
Applicants: ONCOLYTICS BIOTECH INC. [CA/CA]; 301, 1211 Kensington Road, N.W., Calgary, Alberta T2N 3P6 (CA) (For All Designated States Except US).
COFFEY, Matthew, C. [CA/CA]; (CA) (For US Only).
THOMPSON, Bradley, G. [CA/CA]; (CA) (For US Only)
Inventors: COFFEY, Matthew, C.; (CA).
THOMPSON, Bradley, G.; (CA)
Agent: DONAHUE ERNST & YOUNG LLP; Ernst & Young Tower, Toronto-Dominion Centre, 222 Bay Street, Suite 1800, P.O. Box 197, Toronto, Ontario M4K 1H6 (CA)
Priority Data:
60/164,878 12.11.1999 US
Title (EN) VIRUSES FOR THE TREATMENT OF CELLULAR PROLIFERATIVE DISORDERS
(FR) VIRUS POUR LE TRAITEMENT DES TROUBLES DE LA PROLIFERATION CELLULAIRE
Abstract: front page image
(EN)Methods for treating cell proliferative disorders by administering virus to proliferative cells having an activated Ras-pathway are disclosed. The virus is administered so that it ultimately directly contacts proliferating cells having an activated Ras-pathway. Proliferative disorders include but are not limited to neoplasms. The virus is selected from modified adenovirus, modified HSV, modified vaccinia virus and modified parapoxvirus orf virus. Also disclosed are methods for treating cell proliferative disorders by further administering an immunosuppressive agent.
(FR)Cette invention se rapporte à des procédés qui servent à traiter les troubles de la prolifération cellulaire en administrant un virus aux cellules prolifératives comportant un chemin ras activé. Le virus est administré de telle sorte qu'il finit par entrer en contact directement avec les cellules prolifératives ayant un chemin ras activé. Ces troubles de la prolifération cellulaire sont notamment les néoplasmes. Le virus est choisi parmi des adénovirus modifiés, des virus HSV modifiés, les virus de la vaccine modifiés et les virus orf du parapoxe modifiés. Cette invention concerne également des procédés servant à traiter les troubles de la prolifération cellulaire en administrant également un agent immunosuppresseur.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)