Search International and National Patent Collections

1. (WO2001035927) TOPICAL APPLICATION OF MUSCARINIC ANALGESIC DRUGS SUCH AS NEOSTIGMINE

Pub. No.:    WO/2001/035927    International Application No.:    PCT/US2000/031416
Publication Date: Sat May 26 01:59:59 CEST 2001 International Filing Date: Fri Nov 17 00:59:59 CET 2000
IPC: A61K 9/70
A61K 31/27
A61K 47/24
Applicants: EL KHOURY, George, F.
Inventors: EL KHOURY, George, F.
Title: TOPICAL APPLICATION OF MUSCARINIC ANALGESIC DRUGS SUCH AS NEOSTIGMINE
Abstract:
The invention is directed to methods, pharmaceutical compositions, and medical dressings for the topical administration of analgesic drugs which affects peripheral muscarinic receptors such as neostigmine. In particular, the invention relates to topical administration of an analgesic agent, e.g., neostigmine, optionally in admixture with a skin- or mucosal-specific penetration enhancer, to produce a localized analgesic effect in inflamed or non-inflamed skin or mucosal tissue, and without a transdermal or transmucosal migration of the agent, e.g., into the central nervous system.