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1. (WO2001035900) SYNTHESIS OF 3-ETHOXY-4-ETHOXYCARBONYL PHENYL ACETIC ACID, A KEY ACID SYNTHON OF REPAGLINIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/035900 International Application No.: PCT/IB2000/001288
Publication Date: 25.05.2001 International Filing Date: 11.09.2000
IPC:
C07C 67/10 (2006.01) ,C07C 67/313 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
67
Preparation of carboxylic acid esters
10
by reacting carboxylic acids or symmetrical anhydrides with ester groups or with a carbon-halogen bond
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
C
ACYCLIC OR CARBOCYCLIC COMPOUNDS
67
Preparation of carboxylic acid esters
30
by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
313
by introduction of doubly bound oxygen containing functional groups, e.g. carboxyl groups
Applicants: SALMAN, Mohammad[IN/IN]; IN (UsOnly)
BABU, Suresh, J.[IN/IN]; IN (UsOnly)
RAY, Purna, C.[IN/IN]; IN (UsOnly)
BISWAS, Sujay[IN/IN]; IN (UsOnly)
KUMAR, Naresh[IN/IN]; IN (UsOnly)
RANBAXY LABORATORIES LIMITED[IN/IN]; 19, Nehru Place New Delhi 110 019, IN (AllExceptUS)
Inventors: SALMAN, Mohammad; IN
BABU, Suresh, J.; IN
RAY, Purna, C.; IN
BISWAS, Sujay; IN
KUMAR, Naresh; IN
Common
Representative:
RANBAXY LABORATORIES LIMITED; Jayadeep R. Deshmukh Suite 2100 600 College Road East Princeton, NJ 08540, US
Priority Data:
1483/DEL/9916.11.1999IN
Title (EN) SYNTHESIS OF 3-ETHOXY-4-ETHOXYCARBONYL PHENYL ACETIC ACID, A KEY ACID SYNTHON OF REPAGLINIDE
(FR) SYNTHESE D'ACIDE ACETIQUE 3-ETHOXY-4-ETHOXYCARBONYL PHENYLE, UNE SYNTHONE ACIDE CLE DU REPAGLINIDE
Abstract:
(EN) The present invention relates to a new and industrially advantageous process for the preparation of 3-ethoxy-4-ethoxycarbonyl-phenyl acetic acid. This compound is a key intermediate for the synthesis of Repaglinide, an oral hypoglycemic agent.
(FR) La présente invention concerne un nouveau procédé présentant des avantages du point de vue industriel, servant à la préparation d'acide acétique 3-éthoxy-4-éthoxycarbonyl-phényle. Ce composé est un intermédiaire clé dans la synthèse du répaglinide, un agent hypoglycémique oral.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)