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Machine translation
1. (WO2001034836) SUSCEPTIBILITY LOCUS FOR OSTEOARTHRITIS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/034836 International Application No.: PCT/GB2000/004261
Publication Date: 17.05.2001 International Filing Date: 06.11.2000
Chapter 2 Demand Filed: 01.06.2001
IPC:
C12Q 1/68 (2006.01)
Applicants: SYKES, Bryan[GB/GB]; GB (UsOnly)
LOUGHLIN, John[GB/GB]; GB (UsOnly)
CARR, Andrew[GB/GB]; GB (UsOnly)
CATALYST BIOMEDICA LTD[GB/GB]; 183 Euston Road Greater London NW1 2BE, GB (AllExceptUS)
Inventors: SYKES, Bryan; GB
LOUGHLIN, John; GB
CARR, Andrew; GB
Agent: BRASNETT, Adrian, H.; Mewburn Ellis York House 23 Kingsway London WC2B 6HP, GB
Priority Data:
9926414.508.11.1999GB
Title (EN) SUSCEPTIBILITY LOCUS FOR OSTEOARTHRITIS
(FR) LOCUS DE PREDISPOSITION LIE A L'ARTHROSE
Abstract:
(EN) Osteoarthritis (OA) is a debilitating disease involving degeneration of the articular cartilage of synovial joints. It is known that the susceptibility of an individual to osteroarthritis is affected by various loci within the genome. This invention relates to the identification, using genome-wide linkage analysis, of chromosomal regions on chromosome (16) which are linked to genetic sequences which affect susceptibility to osteoarthritis. Methods and means of determining the susceptibility to osteoarthritis of an individual are provided.
(FR) L'arthrose est une maladie débilitante impliquant la dégénération du cartilage articulaire des diarthroses. Il est bien connu que la prédisposition d'un individu à l'arthrose provient des différents locus à l'intérieur du génome. La présente invention concerne l'identification, au moyen d'une analyse des liaisons sur l'ensemble du génome, des régions chromosomiques sur un chromosome (16) qui sont liées à des séquences génétiques affectant la prédisposition à l'arthrose. L'invention concerne également des procédés et des moyens de détermination de la prédisposition d'un individu à l'arthrose.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)