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1. (WO2001034808) METHOD OF LARGE-SCALE PRODUCTION AND METHOD OF TESTING OF THE BIOLOGICAL ACTIVITY OF A SUBSTANCE FROM SOYBEAN

Pub. No.:    WO/2001/034808    International Application No.:    PCT/US2000/031211
Publication Date: Fri May 18 01:59:59 CEST 2001 International Filing Date: Mon Nov 13 00:59:59 CET 2000
IPC: C07K 14/415
C12P 21/00
Applicants: FILGEN BIOSCIENCES, INC.
Inventors: GALVEZ, Alfredo, F.
Title: METHOD OF LARGE-SCALE PRODUCTION AND METHOD OF TESTING OF THE BIOLOGICAL ACTIVITY OF A SUBSTANCE FROM SOYBEAN
Abstract:
The lunasin peptide has been shown to exhibit inhibitory effects against malignant transformation of cells induced by chemical carcinogens and viral oncogenes. The present invention relates to a method for large-scale production of lunasin using recombinant DNA technology. The invention also includes a method for a rapid, in vitro transformation assay to detect and quantify the biological activity of this cancer preventive peptide.