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1. (WO2001034766) PROTEIN MONITORING THE ACTIVITY OF SMALL GTP-BINDING PROTEIN
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/034766 International Application No.: PCT/JP2001/000631
Publication Date: 17.05.2001 International Filing Date: 31.01.2001
IPC:
C07K 19/00 (2006.01) ,C12N 15/62 (2006.01) ,C12N 5/10 (2006.01) ,A01K 67/033 (2006.01) ,C12Q 1/02 (2006.01) ,G01N 33/566 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
19
Hybrid peptides
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
11
DNA or RNA fragments; Modified forms thereof
62
DNA sequences coding for fusion proteins
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5
Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
10
Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
A HUMAN NECESSITIES
01
AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
K
ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
67
Rearing or breeding animals, not otherwise provided for; New breeds of animals
033
Rearing or breeding invertebrates; New breeds of invertebrates
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
02
involving viable micro-organisms
G PHYSICS
01
MEASURING; TESTING
N
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33
Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48
Biological material, e.g. blood, urine; Haemocytometers
50
Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53
Immunoassay; Biospecific binding assay; Materials therefor
566
using specific carrier or receptor proteins as ligand binding reagent
Applicants:
MATSUDA, Michiyuki [JP/JP]; JP
Inventors:
MATSUDA, Michiyuki; JP
Agent:
HOSODA, Yoshinori; c/o Hosoda International Patent Office Otemae M2 Bldg., 8-1, Tanimachi 2-chome, Chuo-ku Osaka-shi, Osaka 540-0012, JP
Priority Data:
2000-24591014.08.2000JP
Title (EN) PROTEIN MONITORING THE ACTIVITY OF SMALL GTP-BINDING PROTEIN
(FR) PROTEINE SURVEILLANT L'ACTIVITE D'UNE PETITE PROTEINE DE FUSION GTP
(JA) 低分子量GTP結合タンパク質の活性モニタータンパク質
Abstract:
(EN) A protein monitoring the activity of a small GTP-binding protein which makes it possible to measure the activation of a non-invasive small GTP-binding protein; a gene encoding the above protein; an expression vector containing the above gene; a transformed cell and a transgenic animal expressing the above protein and carrying the above expression vector which is useful in measuring the activation of a non-invasive small GTP-binding protein; and a method of measuring the activation of a small GTP-binding protein by using the above protein.
(FR) Cette invention concerne une protéine surveillant l'activité d'une petite protéine de fusion GTP et de mesurer l'activation d'une petite protéine GTP non invasive ; un vecteur d'expression renfermant le gène susmentionné ; une cellule transformée et un animal transgénique exprimant la protéine ci-dessus et portant le vecteur d'expression utile pour mesurer l'activation d'une petite protéine de fusion GTP non invasive; et méthode de mesure de l'activation d'une petite protéine de fusion GTP au moyen de la protéine susmentionnée.
(JA) 本発明は非侵襲な低分子量GTP結合タンパク質の活性化の測定を可能にする低分子量GTP結合タンパク質の活性モニタ-タンパク質;該タンパク質をコ-ドする遺伝子;該遺伝子を含む発現ベクタ-;前記タンパク質を発現し、非侵襲な低分子量GTP結合タンパク質の活性化の測定に有用な前記発現ベクタ-を保持する形質転換された細胞およびトランスジェニック動物;ならびに前記タンパク質を用いる低分子量GTP結合タンパク質の活性化を測定する方法を提供するものである。
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)