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1. (WO2001033217) MONITORING THE ACTIVITY OF FACTOR XA INHIBITORS

Pub. No.:    WO/2001/033217    International Application No.:    PCT/EP2000/010646
Publication Date: Fri May 11 01:59:59 CEST 2001 International Filing Date: Sun Oct 29 01:59:59 CEST 2000
IPC: C12Q 1/56
Applicants: AVENTIS PHARMA DEUTSCHLAND GMBH
FUNG-HWEI, Valeria, Chu
Inventors: FUNG-HWEI, Valeria, Chu
Title: MONITORING THE ACTIVITY OF FACTOR XA INHIBITORS
Abstract:
The invention relates to a method of monitoring the effect of a direct of indirect Factor Xa inhibitors comprising the steps of collecting a plasma sample from a patient, adding a solution of Russell's viper venom to the plasma sample and measuring the clotting time or the residual FXa activity chromogenically.