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1. (WO2001033199) UNIVERSAL FLUORESCENT SENSORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/033199    International Application No.:    PCT/GB2000/004255
Publication Date: 10.05.2001 International Filing Date: 06.11.2000
Chapter 2 Demand Filed:    03.05.2001    
IPC:
C12Q 1/68 (2006.01)
Applicants: ISIS INNOVATION LIMITED [GB/GB]; Ewert House, Ewert Place, Summertown, Oxford OX2 7SG (GB) (For All Designated States Except US).
FRICKER, Mark, David [GB/GB]; (GB) (For US Only).
VAUX, David, John, Talbutt [GB/GB]; (GB) (For US Only)
Inventors: FRICKER, Mark, David; (GB).
VAUX, David, John, Talbutt; (GB)
Agent: ELLIS-JONES, Patrick, George, Armine; J.A. Kemp & Co., 14 South Square, Gray's Inn, London WC1R 5LX (GB)
Priority Data:
9926336.0 05.11.1999 GB
Title (EN) UNIVERSAL FLUORESCENT SENSORS
(FR) MARQUEURS FLUORESCENTS UNIVERSELS
Abstract: front page image
(EN)A probe comprises: (i) a target binding site peptide which is attached to a first fluorescent polypeptide; (ii) a mimic peptide which is capable of binding to the target binding site peptide and is attached to a second fluorescent polypeptide; and (iii) a linker which connects the two fluorescent polypeptides and which allows the distance between said fluorescent polypeptides to vary, said fluorescent polypeptides being such as to display fluorescence resonance energy transfer (FRET) between them.
(FR)La présente invention concerne un échantillon comprenant: (i) un peptide à site de liaison cible qui est fixé à un premier polypeptide fluorescent; (ii) un peptide mimétique capable de se lier au peptide à site de liaison cible et fixé à un second polypeptide fluorescent; et (iii) un agent de liaison qui sert à relier les deux polypeptides fluorescents et qui permet à la distance entre lesdits polypeptides fluorescents de varier, lesdits polypeptides fluorescents étant en mesure de réaliser entre eux le transfert d'énergie de fluorescence par résonance (fluorescence resonance energy transfer / FRET).
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)