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Machine translation
1. (WO2001032683) PRODUCTION OF POLYMORPHIC FORMS I AND II OF FINASTERIDE BY COMPLEXATION WITH GROUP I OR II METAL SALTS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/032683 International Application No.: PCT/CA1999/001017
Publication Date: 10.05.2001 International Filing Date: 01.11.1999
Chapter 2 Demand Filed: 28.05.2001
IPC:
C07J 73/00 (2006.01)
Applicants: SLEMON, Clarke[CA/CA]; CA (UsOnly)
TORCAN CHEMICAL LTD.[CA/CA]; 110 Industrial Parkway North Aurora, Ontario L4G 3H4, CA (AllExceptUS)
Inventors: SLEMON, Clarke; CA
Agent: HIRONS, Robert, G.; Ridout & Maybee 150 Metcalfe Street 18th Floor Ottawa, Ontario K2P 1P1, CA
Priority Data:
Title (EN) PRODUCTION OF POLYMORPHIC FORMS I AND II OF FINASTERIDE BY COMPLEXATION WITH GROUP I OR II METAL SALTS
(FR) PRODUCTION DE FORMES POLYMORPHES I ET II DE FINASTERIDE PAR COMPLEXATION AVEC DES SELS DE METAUX DE GROUPE I OU II
Abstract:
(EN) Polymorphic Form (I) finasteride is prepared by first forming a substantially insoluble complex of finasteride and a Group (I) or Group (II) metal salt, such as lithium bromide, and then dissociating the complex by dissolving away the salt component with water, so as to obtain substantially pure Form (I) polymorphic crystalline finasteride.
(FR) L'invention concerne une forme polymorphe (I) de finastéride préparée par formation préalable d'un complexe sensiblement insoluble de finastéride et d'un sel d'un métal de groupe (I) ou de groupe (II), tel que le bromure de lithium, puis par dissociation du complexe obtenue en dissolvant le composant salin avec de l'eau, de manière à obtenir une forme polymorphe (I) crystalline de finastéride sensiblement pure.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)