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1. (WO2001032665) NEW RUTHENIUM METAL LIGAND COMPLEXES

Pub. No.:    WO/2001/032665    International Application No.:    PCT/US2000/041758
Publication Date: Fri May 11 01:59:59 CEST 2001 International Filing Date: Wed Nov 01 00:59:59 CET 2000
IPC: C07F 15/00
Applicants: FLUORRX, INC.
MURTAZA, Zakir
Inventors: MURTAZA, Zakir
Title: NEW RUTHENIUM METAL LIGAND COMPLEXES
Abstract:
A fluorescent metal ligand complex includes a transition metal associated with a complement of diamine ligands, which may be the same or different, one of which is amino reactive for attachment to biological molecules. The surprisingly long lifetime and high anisotropy ratio of the complexes make them especially useful in fluorescence polarization assays and in fluorescence resonance energy transfer assays.