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1. (WO2001032164) INHIBITOR FOR 20-HETE-YIELDING ENZYME

Pub. No.:    WO/2001/032164    International Application No.:    PCT/JP2000/007694
Publication Date: Fri May 11 01:59:59 CEST 2001 International Filing Date: Thu Nov 02 00:59:59 CET 2000
IPC: A61K 31/155
A61K 31/166
A61K 31/18
A61K 31/245
A61K 31/275
A61K 31/341
A61K 31/343
A61K 31/351
A61K 31/352
A61K 31/357
A61K 31/36
A61K 31/381
A61K 31/40
A61K 31/403
A61K 31/4035
A61K 31/404
A61K 31/415
A61K 31/416
A61K 31/4192
A61K 31/42
A61K 31/4245
A61K 31/426
A61K 31/428
A61K 31/429
A61K 31/433
A61K 31/44
A61K 31/4402
A61K 31/445
A61K 31/4453
A61K 31/45
A61K 31/472
A61K 31/502
A61K 31/505
A61K 31/522
A61K 31/5375
C07C 311/21
C07C 311/46
C07C 317/40
C07C 323/12
C07C 323/19
C07C 323/41
C07C 323/52
C07C 323/65
C07C 335/26
Applicants: TAISHO PHARMACEUTICAL CO., LTD.

SATO, Masakazu

MIYATA, Noriyuki

ISHII, Takaaki

KOBAYASHI, Yuko

AMADA, Hideaki

Inventors: SATO, Masakazu

MIYATA, Noriyuki

ISHII, Takaaki

KOBAYASHI, Yuko

AMADA, Hideaki

Title: INHIBITOR FOR 20-HETE-YIELDING ENZYME
Abstract:
An inhibitor for 20-hydroxyeicosatetraenoic acid production which comprises as the active ingredient a specific hydroxyformamidine derivative or a pharmacologically acceptable salt thereof. It is useful especially as a remedy for kidney diseases, cerebrovascular diseases, or circulatory diseases. The novel hydroxyformamidine derivative or pharmacologically acceptable salt thereof is also provided.