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1. (WO2001032144) DRY POWDER COMPOSITIONS HAVING IMPROVED DISPERSIVITY

Pub. No.:    WO/2001/032144    International Application No.:    PCT/US2000/009785
Publication Date: Fri May 11 01:59:59 CEST 2001 International Filing Date: Thu Apr 13 01:59:59 CEST 2000
IPC: A61K 47/18
Applicants: INHALE THERAPEUTIC SYSTEMS, INC.
LECHUGA-BALLESTEROS, David
KUO, Mei-Chang
Inventors: LECHUGA-BALLESTEROS, David
KUO, Mei-Chang
Title: DRY POWDER COMPOSITIONS HAVING IMPROVED DISPERSIVITY
Abstract:
The present invention provides a highly dispersible formulation comprising an active agent and a dipeptide or tripeptide comprising at least two leucyl residues. The composition of the invention possesses superior aerosol properties and is thus preferred for aerosolized administration to the lung. Also provided are a method for (i) increasing the dispersibility of an active-agent containing formulation for administration to the lung, and (ii) delivery of the composition to the lungs of a subject.