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1. (WO2001031002) A NOVEL POLYPEPTIDE, A HUMAN STEROL REGULATORY CONSTITUENT BINDING PROTEIN CUTTING ACTIVE PROTEIN 22 AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/031002 International Application No.: PCT/CN2000/000389
Publication Date: 03.05.2001 International Filing Date: 27.10.2000
Chapter 2 Demand Filed: 21.05.2001
IPC:
A61K 38/00 (2006.01) ,C07K 14/47 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
46
from vertebrates
47
from mammals
Applicants:
MAO, Yumin [CN/CN]; CN (UsOnly)
XIE, Yi [CN/CN]; CN (UsOnly)
SHANGHAI BIO ROAD GENE DEVELOPMENT LTD. [CN/CN]; 12th Floor 3rd Building N°. 1111, Zhongshan Bei Er Road Shanghai 200092, CN (AllExceptUS)
Inventors:
MAO, Yumin; CN
XIE, Yi; CN
Agent:
SHANGHAI ZHI XIN PATENT AGENT LTD.; 10/F, Italy Building 446 Zhao Jia Bang Road Shanghai 200031, CN
Priority Data:
99 1 19857.327.10.1999CN
Title (EN) A NOVEL POLYPEPTIDE, A HUMAN STEROL REGULATORY CONSTITUENT BINDING PROTEIN CUTTING ACTIVE PROTEIN 22 AND THE POLYNUCLEOTIDE ENCODING THE POLYPEPTIDE
(FR) NOUVEAU POLYPEPTIDE, PROTEINE HUMAINE ACTIVE 22 (SCAP) IMPLIQUEE DANS LA COUPURE DES PROTEINES SREBP, ET POLYNUCLEOTIDE CODANT POUR CE POLYPEPTIDE
Abstract:
(EN) The present invention discloses a novel polypeptide, a human sterol regulatory constituent binding protein cutting active protein 22, the polynucleotide encoding the polypeptide and the method for producing the polypeptide by DNA recombinant technology. The invention also discloses the uses of the polypeptide in methods for treating various diseases, such as malignant tumour, hemopathy, HIV infection, immunological disease, and various inflammation, etc. The invention also discloses the agonists against the polypeptide and the therapeutic action thereof. The invention also discloses the uses of the polynucleotide encoding the novel human sterol regulatory constituent binding protein cutting active protein 22.
(FR) L'invention concerne un nouveau polypeptide, une protéine humaine active 22 (SCAP) impliquée dans la coupure des protéines SREBP, et un polynucléotide codant pour ce polypeptide ainsi qu'un procédé d'obtention de ce polypeptide par des techniques recombinantes d'ADN. L'invention concerne en outre les applications de ce polypeptide dans le traitement de maladies, notamment des tumeurs malignes, de l'hémopathie, de l'infection par VIH, de maladies immunitaires et de diverses inflammations. L'invention concerne aussi l'antagoniste agissant contre le polypeptide et son action thérapeutique ainsi que les applications de ce polynucléotide codant pour la protéine humaine active 22 (SCAP) impliquée dans la coupure des protéines SREBP.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)