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1. (WO2001030994) NOVEL RHODOCOCCUS, RHODOCOCCUS-ORIGIN NITRILASE GENE, NITRILEHYDRATASE GENE AND AMIDASE GENE AND PROCESS FOR PRODUCING CARBOXYLIC ACIDS BY USING THE SAME

Pub. No.:    WO/2001/030994    International Application No.:    PCT/JP2000/007464
Publication Date: Fri May 04 01:59:59 CEST 2001 International Filing Date: Thu Oct 26 01:59:59 CEST 2000
IPC: C12N 9/78
C12P 7/40
Applicants: SHOWA DENKO K.K.

AOKI, Hirobumi

KAMACHI, Harumi

Inventors: AOKI, Hirobumi

KAMACHI, Harumi

Title: NOVEL RHODOCOCCUS, RHODOCOCCUS-ORIGIN NITRILASE GENE, NITRILEHYDRATASE GENE AND AMIDASE GENE AND PROCESS FOR PRODUCING CARBOXYLIC ACIDS BY USING THE SAME
Abstract:
A novel rhodococcus and a process for producing carboxylic acids by hydrolyzing cyano group of nitrile compounds by using this bacterium. A process for producing carboxylic acids (in particular, cyanocarboxylic acids) by using transformants having been transformed by plasmids containing rhodococcus-origin nitrilase gene, nitrilehydratase gene and amidase gene showing an excellent site-selectivity to cyano group of aromatic polynitrile compounds; these transformants, plasmids, genes and a process for producing enzymes by using these transformants; and the enzymes thus obtained. The carboxylic acids (in particular, cyanocarboxylic acids) thus obtained are useful as starting materials in the synthesis of drugs, pesticides, dyes and other chemical products.