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1. (WO2001030971) NOVEL MOLECULES AND THE CARD-RELATED PROTEIN FAMILY AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/030971    International Application No.:    PCT/US2000/029643
Publication Date: 03.05.2001 International Filing Date: 26.10.2000
Chapter 2 Demand Filed:    24.05.2001    
IPC:
A61K 38/00 (2006.01), C07K 14/47 (2006.01)
Applicants: MILLENNIUM PHARMACEUTICALS, INC. [US/US]; 75 Sidney Street, Cambridge, MA 02139 (US) (For All Designated States Except US).
BERTIN, John [US/US]; (US) (For US Only).
ROBISON, Keith, E. [US/US]; (US) (For US Only)
Inventors: BERTIN, John; (US).
ROBISON, Keith, E.; (US)
Agent: MEIKLEJOHN, Anita, L.; Fish & Richardson P.C., 225 Franklin Street, Boston, MA 02110-2804 (US)
Priority Data:
60/161,822 27.10.1999 US
Title (EN) NOVEL MOLECULES AND THE CARD-RELATED PROTEIN FAMILY AND USES THEREOF
(FR) NOUVELLES MOLECULES DE LA FAMILLE DES PROTEINES SE RAPPORTANT AUX CARD ET LEURS UTILISATIONS
Abstract: front page image
(EN)Novel CARD-12 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated CARD-12 proteins, the invention further provides CARD-12, fusion proteins, antigenic peptides and anti-CARD-12 antibodies. The invention also provides CARD-12 nucleic acid molecules, recombinant expression vectors containing a nucleic acid molecule of the invention, host cells into which the expression vectors have been introduced and non-human transgenic animals in which a CARD-12 gene has been introduced or disrupted. Diagnostic, screening and therapeutic methods utilizing compositions of the inventions are also provided.
(FR)La présente invention concerne des polypeptides CARD-12, des protéines et des molécules d'acide nucléique. Outre les protéines CARD-12 isolées, l'invention concerne également les CARD-12, des protéines de fusion, des peptides antigènes, et des anticorps anti-CARD-12. L'invention concerne aussi des molécules d'acide nucléique CARD-12, des vecteurs d'expression de recombinaison contenant une molécule d'acide nucléique de l'invention, des cellules hôtes dans lesquelles ces vecteurs d'expression ont été introduits, et des animaux transgéniques non-humains dans lesquels on a introduit ou interrompu un gène CARD-12. L'invention concerne enfin l'utilisation de compositions de l'invention à des fins de diagnostic, à des fins de recherche systématique, et à des fins thérapeutiques.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)