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1. (WO2001030797) ANTISENSE MODULATION OF METHIONINE AMINOPEPTIDASE 2 EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/030797    International Application No.:    PCT/US2000/029090
Publication Date: 03.05.2001 International Filing Date: 20.10.2000
Chapter 2 Demand Filed:    22.05.2001    
IPC:
A61K 38/00 (2006.01), C12N 15/11 (2006.01), C12Q 1/68 (2006.01)
Applicants: ISIS PHARMACEUTICALS, INC. [US/US]; 2292 Faraday Avenue, Carlsbad, CA 92008 (US) (For All Designated States Except US).
MONIA, Brett, P. [US/US]; (US) (For US Only).
WYATT, Jacqueline, R. [US/US]; (US) (For US Only)
Inventors: MONIA, Brett, P.; (US).
WYATT, Jacqueline, R.; (US)
Agent: LICATA, Jane, Massey; Law Offices of Jane Massey Licata, 66 E. Main Street, Marlton, NJ 08053 (US)
Priority Data:
09/428,584 27.10.1999 US
Title (EN) ANTISENSE MODULATION OF METHIONINE AMINOPEPTIDASE 2 EXPRESSION
(FR) MODULATION ANTISENS DE L'EXPRESSION DE L'AMINOPEPTIDASE 2DE METHIONINE
Abstract: front page image
(EN)Antisense compounds, compositions and methods are provided for modulating the expression of methionine aminopeptidase 2. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding methionine aminopeptidase 2. Methods of using these compounds for modulation of methionine aminopeptidase 2 expression and for treatment of diseases associated with expression of methionine aminopeptidase 2 are provided.
(FR)La présente invention concerne ces composés antisens, des compositions et des techniques permettant de moduler l'expression de l'aminopeptidase 2 de méthionine. Ces compositions comprennent des composés antisens, en particulier des oligonucléotides antisens, des acides nucléiques ciblés codant pour l'aminopeptidase 2 de méthionine. Cette invention concerne aussi des techniques d'utilisation de ces composés permettant la modulation de l'expression de l'aminopeptidase 2 de méthionine et le traitement de maladies associées à l'expression de l'aminopeptidase 2 de méthionine.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)