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1. (WO2001030759) SODIUM-HYDROGEN EXCHANGER TYPE 1 INHIBITOR CRYSTALS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/030759 International Application No.: PCT/IB2000/001460
Publication Date: 03.05.2001 International Filing Date: 09.10.2000
Chapter 2 Demand Filed: 08.02.2001
IPC:
C07D 401/04 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
401
Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02
containing two hetero rings
04
directly linked by a ring-member-to-ring- member bond
Applicants:
BROSTROM, Lyle, Robinson [US/US]; US (UsOnly)
CONNOLLY, Terrence, Joseph [CA/CA]; CA (UsOnly)
LI, Zheng, Jane [US/US]; US (UsOnly)
ORRILL, Susan, Lee [US/US]; US (UsOnly)
SHAH, Bharat, Kiritkumar [US/US]; US (UsOnly)
PFIZER PRODUCTS INC. [US/US]; Eastern Point Road Groton, CT 06340, US (AllExceptUS)
Inventors:
BROSTROM, Lyle, Robinson; US
CONNOLLY, Terrence, Joseph; CA
LI, Zheng, Jane; US
ORRILL, Susan, Lee; US
SHAH, Bharat, Kiritkumar; US
Agent:
SPIEGEL, Allen, J.; Pfizer Inc. 235 East 42nd Street New York, NY 10017, US
Priority Data:
60/162,37429.10.1999US
Title (EN) SODIUM-HYDROGEN EXCHANGER TYPE 1 INHIBITOR CRYSTALS
(FR) CRISTAUX D'INHIBITEURS DE L'ECHANGEUR SODIUM-HYDROGENE DE TYPE 1
Abstract:
(EN) NHE-1 inhibitor crystal of Formula (I), methods of using such NHE-1 inhibitor crystal and pharmaceutical compositions containing such NHE-1 inhibitor crystal. The NHE-1 inhibitor crystal is useful for the reduction of tissue damage resulting from tissue ischemia.
(FR) L'invention concerne des cristaux d'inhibiteurs de l'échangeur sodium-hydrogène de type 1 (NHE-1), les méthodes d'utilisation desdits cristaux d'inhibiteurs NHE-1, et des compositions pharmaceutiques renfermant les cristaux d'inhibiteurs NHE-1. Ces cristaux d'inhibiteurs NHE-1 sont utilisés pour limiter les lésions tissulaires résultant de l'ischémie tissulaire.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)