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1. (WO2001030389) WOUND CONTRACTION INHIBITORS

Pub. No.:    WO/2001/030389    International Application No.:    PCT/JP2000/007476
Publication Date: Fri May 04 01:59:59 CEST 2001 International Filing Date: Thu Oct 26 01:59:59 CEST 2000
IPC: A61K 38/57
Applicants: JAPAN TISSUE ENGINEERING CO., LTD.

SUMI, Yukio

HATA, Kenichiro

UEDA, Minoru

MURAMATSU, Hisako

MURAMATSU, Takashi

Inventors: SUMI, Yukio

HATA, Kenichiro

UEDA, Minoru

MURAMATSU, Hisako

MURAMATSU, Takashi

Title: WOUND CONTRACTION INHIBITORS
Abstract:
Wound contraction inhibitors containing a secretory leukocyte protease inhibitor (SLPI) as the active ingredient. The SLPI concentration in these drugs preferably ranges from 1 to 5000 ng/ml, still preferably from 1 to 100 ng/ml. These drugs may be in the form of external preparations which contain the SLPI as the active ingredient and a base. It is also possible that these drugs are in the form of injections containing the SLPI as the active ingredient. It is favorable that the above-described external preparations further contain preservatives while the above-described injections further contain stabilizers (antioxidants), preservatives and soothing agents.