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1. (WO2001030385) ADJUVANTS FOR NUCLEIC ACID VACCINES

Pub. No.:    WO/2001/030385    International Application No.:    PCT/NL2000/000773
Publication Date: Fri May 04 01:59:59 CEST 2001 International Filing Date: Fri Oct 27 01:59:59 CEST 2000
IPC: A61K 39/39
A61K 48/00
C12N 15/86
C12N 15/87
Applicants: ID-LELYSTAD, INSTITUUT VOOR DIERHOUDERIJ EN DIERGEZONDHEID B.V.
VAN ROOIJ, Eugene, Marie, Antoine
HILGERS, Lucas, Alfonsus, Theodorus
Inventors: VAN ROOIJ, Eugene, Marie, Antoine
HILGERS, Lucas, Alfonsus, Theodorus
Title: ADJUVANTS FOR NUCLEIC ACID VACCINES
Abstract:
The present invention relates to the field of vaccination. In particular, the invention relates to immunization by administration of a nucleic acid encoding a gene product (e.g. proteins, glycoproteins, lipoproteins) of an infectious or non-infectious agent. In accordance with the invention it has been found that dimethyldialkylammonium salts enhance the immune response of a nucleic acid vaccine.