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1. (WO2001030362) RIBOZYME THERAPY FOR THE TREATMENT OF PROLIFERATIVE SKIN AND EYE DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/030362    International Application No.:    PCT/US2000/029500
Publication Date: 03.05.2001 International Filing Date: 26.10.2000
IPC:
A61K 38/00 (2006.01), C12N 15/11 (2006.01)
Applicants: IMMUSOL INCORPORATED [US/US]; 10790 Roselle Street, San Diego, CA 92121 (US).
ROBBINS, Joan, M. [US/US]; (US) (For US Only).
TRITZ, Richard [US/US]; (US) (For US Only)
Inventors: ROBBINS, Joan, M.; (US).
TRITZ, Richard; (US)
Agent: MCMASTERS, David, D.; Seed Intellectual Property Law Group PLLC, Suite 6300, 701 Fifth Avenue, Seattle, WA 98104-7092 (US)
Priority Data:
60/161,532 26.10.1999 US
Title (EN) RIBOZYME THERAPY FOR THE TREATMENT OF PROLIFERATIVE SKIN AND EYE DISEASES
(FR) THERAPIE RIBOZYMIQUE DESTINEE AU TRAITEMENT DE MALADIES PROLIFERANTES DE LA PEAU ET DES YEUX
Abstract: front page image
(EN)As an effective therapy for proliferative skin and eye diseases such as psoriasis and proliferative diabetic retinopathy, this invention provides ribozymes and ribozyme delivery systems which cleave RNA encoding cytokines involved in inflammation, matrix metalloproteinases, a cyclin, a cell-cycle dependent kinase, a growth factor, or a reductase.
(FR)L'invention concerne une thérapie efficace dirigée contre les maladies proliférantes de la peau et des yeux, telles que le psoriasis et la rétinopathie diabétique proliférante. Elle fait intervenir des ribozymes et des systèmes d'administration de ribozymes qui clivent l'ARN codant les cytokines impliquées dans l'inflammation, des métalloprotéinases matricielles, une cycline, une kinase dépendante du cycle cellulaire, un facteur de croissance ou une réductase.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)