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1. (WO2001030325) USE OF A BIS-PEROXOVANADIUM COMPOUND FOR THE TREATMENT OF IMMUNOSUPPRESSED PATIENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/030325 International Application No.: PCT/CA2000/001258
Publication Date: 03.05.2001 International Filing Date: 23.10.2000
Chapter 2 Demand Filed: 04.05.2001
IPC:
A61K 33/24 (2006.01) ,A61K 33/40 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
24
Heavy metals; Compounds thereof
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
33
Medicinal preparations containing inorganic active ingredients
40
Peroxides
Applicants:
TREMBLAY, Michel, J. [CA/CA]; CA (UsOnly)
BARBEAU, Benoit [CA/CA]; CA (UsOnly)
FORTIN, Jean-François [CA/CA]; CA (UsOnly)
VIROCELL INC. [CA/CA]; 925 chemin St-Louis Bureau 400 Québec, Québec G1S 4W6, CA (AllExceptUS)
Inventors:
TREMBLAY, Michel, J.; CA
BARBEAU, Benoit; CA
FORTIN, Jean-François; CA
Agent:
CÔTÉ, France ; Swabey Ogilvy Renault Suite 1600 1981 McGill College Avenue Montréal, Québec H3A 2Y3, CA
Priority Data:
60/161,35426.10.1999US
Title (EN) USE OF A BIS-PEROXOVANADIUM COMPOUND FOR THE TREATMENT OF IMMUNOSUPPRESSED PATIENTS
(FR) UTILISATION D'UN INHIBITEUR DE LA PHOSPHOTYROSYLPHOSPHATASE DANS LE TRAITEMENT DE PATIENTS IMMUNODEPRIMES
Abstract:
(EN) The present invention provides a method for restoring the immune functions and the overall immune response by administration of a bis-peroxovanadium (bpV) compound, a potent class of phosphotyrosyl phosphatase inhibitors. The method can be utilized in treating individuals afflicted with immune disorders or for the treatment of patients suffering from infections caused by viruses that destroy the natural immune response, such as the human immunodeficiency virus (HIV). The bpV compound may be used in combination with various immunomodulators and/or antiviral agents. The present invention also relates to the use of such bpV compound for restoring the immune functions and the overall immune response in a patient in need of such a treatment.
(FR) L'invention concerne un procédé de restauration des fonctions immunes et de la réponse globale immune, ce procédé consistant à administrer un composé bis-peroxovanadium (bpV) faisant partie d'une famille de puissants inhibiteurs de la phosphotyrosylphosphatase. On peut utiliser ce procédé pour traiter des individus présentant des pathologies d'ordre immunitaire ou dans le traitement de patients soufrant d'infections provoquées par des virus détruisant la réponse immune naturelle, tels que le virus du syndrome immunodéficitaire acquis. Ce composé bpV peut s'utiliser en combinaison avec divers immunomodulateurs et/ou des agents antiviraux. L'invention concerne également l'utilisation d'un tel composé bpV, dans la restauration des fonctions immunes et de la réponse immune globale, chez un patient nécessitant un tel traitement.
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Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)