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1. (WO2001029562) A METHOD FOR THE ASSESSMENT OF ALLERGENICITY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/029562    International Application No.:    PCT/DK2000/000579
Publication Date: 26.04.2001 International Filing Date: 13.10.2000
Chapter 2 Demand Filed:    08.05.2001    
IPC:
G01N 33/68 (2006.01)
Applicants: NOVOZYMES A/S [DK/DK]; Krogshoejvej 36, DK-2880 Bagsværd (DK)
Inventors: ROGGEN, Erwin, Ludo; (DK).
ERNST, Steffen; (DK)
Priority Data:
PA 1999 01486 15.10.1999 DK
Title (EN) A METHOD FOR THE ASSESSMENT OF ALLERGENICITY
(FR) PROCEDE DE DETERMINATION DE L'ALLERGENICITE
Abstract: front page image
(EN)The invention relates to a method for the assessment of the allergenicity or the toxicity of a test compound and for the screening of at least two compounds simultaneously. The invention also relates to a method of characterising a cell type for the present invention, as well as an assay kit for the high through-put screening of a compound. By contacting a cell culture of at least one cell type of animal origin with the test compound and measuring cytokine responses, the allergenicity of the test compound can be assessed.
(FR)L'invention concerne un procédé servant à déterminer l'allergénicité ou la toxicité d'un composé d'essai, et à cribler simultanément au moins deux composés. L'invention concerne également un procédé de caractérisation d'un type de cellule, de même qu'une trousse de dosage destinée au criblage, à un rendement élevé, d'un composé. La mise en contact d'une culture de cellules avec au moins un type de cellule d'origine animale, au moyen de composé d'essai, et la mesure des réponses des cytokines permettent de déterminer l'allergénicité du composé d'essai.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)