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Machine translation
1. (WO2001029196) METHOD OF SELECTING FOR AN INHIBITOR OF DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5 EPIMERASE (RMLC)
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/029196    International Application No.:    PCT/GB2000/004014
Publication Date: 26.04.2001 International Filing Date: 19.10.2000
Chapter 2 Demand Filed:    04.05.2001    
IPC:
C12N 9/90 (2006.01)
Applicants: THE UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS [GB/GB]; 66 North Street, St. Andrews, Fife KY16 9ST (GB) (For All Designated States Except US).
NAISMITH, James, H. [GB/GB]; (GB) (For US Only).
GIRAUD, Marie-France [FR/GB]; (GB) (For US Only)
Inventors: NAISMITH, James, H.; (GB).
GIRAUD, Marie-France; (GB)
Agent: MURGITROYD & COMPANY; 373 Scotland Street, Glasgow G5 8QA (GB)
Priority Data:
9924634.0 19.10.1999 GB
Title (EN) METHOD OF SELECTING FOR AN INHIBITOR OF DTDP-6-DEOXY-D-XYLO-4-HEXULOSE 3,5 EPIMERASE (RMLC)
(FR) PROCEDE DE SELECTION D'UN INHIBITEUR DE LA RMLC
Abstract: front page image
(EN)A method of selecting for an agent which inhibits the enzyme RmlC, said method comprising the steps of providing a three-dimensional structure model of at least one active site of RmlC and using the model for designing and/or evaluating the structure of a potential inhibitory agent. The invention also relates to inhibitors of RmlC, the use of RmlC inhibitors as anti-microbial compounds and a method of selecting or identifying anti-microbial compounds.
(FR)L'invention concerne un procédé de sélection d'un agent inhibant l'enzyme RmlC. Ce procédé comprend les étapes consistant: à fournir un modèle structurel tridimensionnel d'au moins un site actif de la RmlC, puis à utiliser ce modèle pour concevoir et/ou évaluer la structure d'un agent inhibiteur potentiel. L'invention concerne également des inhibiteurs de la RmlC; l'utilisation de ces inhibiteurs comme composés antimicrobiens, et un procédé de sélection ou d'identification de composés antimicrobiens.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)