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Machine translation
1. (WO2001029072) P15?PAF¿ CELL CYCLE PROTEINS ASSOCIATED WITH PCNA, COMPOSITIONS AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/029072    International Application No.:    PCT/US2000/041296
Publication Date: 26.04.2001 International Filing Date: 18.10.2000
Chapter 2 Demand Filed:    18.05.2001    
IPC:
C07K 14/47 (2006.01)
Applicants: RIGEL PHARMACEUTICALS, INC. [US/US]; 240 East Grand Avenue, South San Francisco, CA 94080 (US) (For All Designated States Except US).
LUO, Ying [CN/US]; (US) (For US Only).
YU, PeiWen [--/US]; (US) (For US Only).
HUANG, Betty [US/US]; (US) (For US Only)
Inventors: LUO, Ying; (US).
YU, PeiWen; (US).
HUANG, Betty; (US)
Agent: BREZNER, David, J.; Flehr Hohbach Test Albritton & Herbert LLP, 4 Embarcadero Center, Suite 3400, San Francisco, CA 94111-4187 (US)
Priority Data:
09/420,092 18.10.1999 US
Title (EN) P15?PAF¿ CELL CYCLE PROTEINS ASSOCIATED WITH PCNA, COMPOSITIONS AND METHODS OF USE
(FR) PROTEINES DU CYCLE CELLULAIRE P15?PAF¿ ASSOCIEES A L'ANTIGENE PCNA, COMPOSITIONS ET METHODES D'UTILISATION
Abstract: front page image
(EN)The present invention is directed to novel polypeptides, nucleic acids and related molecules which have an effect on or are related to the cell cycle. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided by the present invention are methods for identifying novel compositions which mediate cell cycle bioactivity, and the use of such compositions in diagnosis and treatment of disease.
(FR)La présente invention concerne des polypeptides, des acides nucléiques et des molécules apparentées qui ont une incidence sur le cycle cellulaire ou qui sont en rapport avec ledit cycle. L'invention concerne également des vecteurs et des cellules hôtes renfermant lesdites séquences d'acides nucléiques, des molécules polypeptidiques chimères comprenant les polypeptides selon l'invention fusionnées à des séquences polypeptidiques hétérologues, des anticorps qui se lient aux polypeptides de l'invention, ainsi que des méthodes d'obtention desdits polypeptides. Cette invention concerne également des méthodes d'identification de compositions qui induisent une bioactivité du cycle cellulaire ainsi que l'utilisation de ces méthodes pour le diagnostic et le traitement de la maladie.
Designated States: AU, CA, JP, US.
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE).
Publication Language: English (EN)
Filing Language: English (EN)