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Machine translation
1. (WO2001028578) A PHARMACEUTICAL COMPOSITION CONTAINING pGLU-GLU-PRO-NH?2¿ AND METHOD FOR TREATING DISEASES AND INJURIES TO THE BRAIN, SPINAL CORD AND RETINA USING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/028578    International Application No.:    PCT/US2000/029278
Publication Date: 26.04.2001 International Filing Date: 20.10.2000
Chapter 2 Demand Filed:    15.05.2001    
IPC:
A61K 38/06 (2006.01), A61K 45/06 (2006.01)
Applicants: WRAIR [US/US]; Walter Reed Army Institute of Research, 14th and Dahlia Streets, NW, Washington, DC 20307 (US) (For All Designated States Except US).
MEYERHOFF, James, L. [US/US]; (US) (For US Only).
KOENIG, Michael, L. [US/US]; (US) (For US Only).
LONG, Joseph, B. [US/US]; (US) (For US Only)
Inventors: MEYERHOFF, James, L.; (US).
KOENIG, Michael, L.; (US).
LONG, Joseph, B.; (US)
Agent: NASH, Caroline; Nash & Titus, LLC, Suite 1000, 3415 Brookeville Road, Brookeville, MD 20833 (US)
Priority Data:
60/160,972 22.10.1999 US
Title (EN) A PHARMACEUTICAL COMPOSITION CONTAINING pGLU-GLU-PRO-NH?2¿ AND METHOD FOR TREATING DISEASES AND INJURIES TO THE BRAIN, SPINAL CORD AND RETINA USING SAME
(FR) COMPOSITION PHARMACEUTIQUE A BASE DE PGLU-GLU-PRO-NH?2¿ ET PROCEDE DE TRAITEMENT DE MALADIES ET DE LESIONS CEREBRALES
Abstract: front page image
(EN)A neuroprotectant composition wherein the active ingredient is pGLU-GLU-PRO-NH?2¿ or a combination of pGLU-GLU-PRO-NH?2¿(EEP) and N-tert-Butyl-$g(a)-(2-sulfophenyl)nitrone(SPBN) or other nitrone. A method of treating and preventing diseases and injuries of the brain, spinal cord and retina is also presented by administering the endogenous tripeptide EEP to a subject as a neuroprotectant or by administering EEP in combination with SPBN or other nitrone.
(FR)L'invention concerne une composition neuroprotectrice dont l'ingrédient actif est pGLU-GLU-PRO-NH?2¿ ou une combinaison de pGLU-GLU-PRO-NH?2¿ (EEP) et de N-tert-Butyl-$g(a)-(2-sulfophényl)nitrone (SPBN) ou d'une autre nitrone. L'invention concerne également un procédé de traitement et de prévention de maladies et de lésions cérébrales, médullaires ou rétiniennes par administration de ce EEP tripeptidique endogène à un sujet en tant que neuroprotecteur, ou par administration de EEP en combinaison avec SPBN ou une autre nitrone.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)