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1. (WO2001028567) AMINOALKYLENEPHOSPHONATES FOR TREATMENT OF BONE DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/028567    International Application No.:    PCT/US2000/028713
Publication Date: 26.04.2001 International Filing Date: 17.10.2000
Chapter 2 Demand Filed:    30.04.2001    
IPC:
A61K 31/662 (2006.01), A61K 31/675 (2006.01), A61K 31/685 (2006.01)
Applicants: THE DOW CHEMICAL COMPANY [US/US]; 2030 Dow Center, Midland, MI 48674 (US) (For All Designated States Except US).
FRANK, R., Keith [US/US]; (US) (For US Only)
Inventors: FRANK, R., Keith; (US)
Agent: KARADZIC, Dragan, J.; Intellectual Property, B-1211, 2301 N. Brazosport Boulevard, Freeport, TX 77541 (US)
Priority Data:
60/160,019 18.10.1999 US
Title (EN) AMINOALKYLENEPHOSPHONATES FOR TREATMENT OF BONE DISORDERS
(FR) AMINOALKYLENEPHOSPHONATES DESTINES AU TRAITEMENT DE MALADIES OSSEUSES
Abstract: front page image
(EN)A method for preventing or minimizing loss of bone mineral in mammals which method comprises administering to a mammal an amount of an aminoalkylenephosphonate which is effective to prevent or minimize loss of bone mineral density. The aminoalkylenephosphonates of the present invention should have at least one R-N(Alk-PO¿3?H¿2?)¿2? group or at least two RR´N-Alk-PO¿3?H¿2? groups wherein R and R´ can be, same or different, aliphatic or cyclic moiety, and Alk is an alkylene group having from 1 to 4 carbon atoms.
(FR)L'invention concerne un procédé destiné à empêcher ou à minimiser la perte de teneur minérale des os chez les mammifères. Ce procédé consiste à administrer à un mammifère une quantité efficace d'un aminoalkylènephosphonate destinée à empêcher ou à minimiser la perte de teneur minérale des os. Les aminoalkylènephosphonates de la présente invention contiennent au moins un groupe R-N(Alk-PO¿3?H¿2?)¿2? ou au moins deux groupes RR´N-Alk-PO¿3?H¿2? dans lesquels R et R' peuvent être égaux ou différents, une fraction aliphatique ou cyclique, et Alk représente un groupe alcoylène possédant 1 à 4 atomes de carbone.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)