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1. (WO2001027305) PROCESS FOR PRODUCING, METHODS AND COMPOSITIONS OF CHOLESTEROL LOWERING AGENTS FROM HIGHER BASIDIOMYCETES MUSHROOMS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/027305    International Application No.:    PCT/US2000/028234
Publication Date: 19.04.2001 International Filing Date: 12.10.2000
Chapter 2 Demand Filed:    04.05.2001    
IPC:
C12N 1/14 (2006.01), C12P 1/02 (2006.01)
Applicants: MEDMYCO, LTD. [IL/IL]; Hahistadrut Avenue 99, P.O. Box 25321, 32150 Haifa (IL) (For All Designated States Except US).
WASSER, Solomon, P. [IL/IL]; (IL).
RESHETNIKOV, Sergey V. G. [UA/UA]; (UA).
KARMALI, Rashida, A. [US/US]; (US) (UG only)
Inventors: WASSER, Solomon, P.; (IL).
RESHETNIKOV, Sergey V. G.; (UA)
Agent: KARMALI, Rashida, A.; Suite 2525, 230 Park Avenue, New York, NY 10169 (US)
Priority Data:
09/419,205 15.10.1999 US
Title (EN) PROCESS FOR PRODUCING, METHODS AND COMPOSITIONS OF CHOLESTEROL LOWERING AGENTS FROM HIGHER BASIDIOMYCETES MUSHROOMS
(FR) PROCESSUS DE PRODUCTION D'HYPOCHOLESTEROLEMIANTS A PARTIR DE CHAMPIGNONS BASIDIOMYCETES SUPERIEURS, PROCEDES ET COMPOSITIONS CORRESPONDANTS
Abstract: front page image
(EN)The present invention describes new and distinct strains of higher Basidiomycetes mushrooms, and a process for growing them in submerged culture. Specifically, the new strains of species of the genus Pleurotus offer superior yields of mushroom biomass and concentrations of biologically active compounds, for example, cholesterol-lowering compounds, lectins, proteins, essential amino acids, vitamins or polysaccharides. The process includes use of defined media and a simple one-step procedure of separating the lovastatin-containing nutriceuticals from culture broth.
(FR)L'invention se rapporte à de nouvelles souches distinctes de champignons Basidiomycètes supérieurs et à un procédé de production de tels champignons dans une culture immergée. L'invention se rapporte particulièrement à de nouvelles souches d'espèces du genre Pleurotus qui permettent d'obtenir de meilleurs rendements de biomasse de champignons et de concentrations de composés biologiquement actifs, par exemple des composés hypocholestérolémiants, des lectines, des protéines, des acides aminés essentiels, des vitamines ou des polysaccharides. L'invention se rapporte en outre à des milieux définis et à une procédure simple permettant d'extraire en une seule étape des nutriceutiques contenant de la lovastatine d'un bouillon de culture.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)