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1. (WO2001025492) HUMAN ANTIBODIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/025492    International Application No.:    PCT/US2000/027237
Publication Date: 12.04.2001 International Filing Date: 02.10.2000
Chapter 2 Demand Filed:    23.04.2001    
C07K 16/00 (2006.01), C07K 16/24 (2006.01), C12N 15/10 (2006.01)
Applicants: BIOSITE DIAGNOSTICS INC. [US/US]; 11030 Roselle Street, Suite D, San Diego, CA 92121 (US) (For All Designated States Except US).
GENPHARM INTERNATIONAL a subsidiary of MEDAREX, INC. [US/US]; 67 Beaver Avenue, Annandale, NJ 08818 (US) (For All Designated States Except US).
BUECHLER, Joe [US/US]; (US) (For US Only).
VALKIRS, Gunars [US/US]; (US) (For US Only).
GRAY, Jeff [US/US]; (US) (For US Only).
LONBERG, Nils [US/US]; (US) (For US Only).
FLORES, Becky, Mar [--/US]; (US) (For US Only)
Inventors: BUECHLER, Joe; (US).
VALKIRS, Gunars; (US).
GRAY, Jeff; (US).
LONBERG, Nils; (US).
FLORES, Becky, Mar; (US)
Agent: LIEBESCHUETZ, Joe; Townsend and Townsend and Crew LLP, Two Embarcadero Center, Eighth Floor, San Francisco, CA 94111 (US)
Priority Data:
60/157,415 02.10.1999 US
09/453,234 01.12.1999 US
Abstract: front page image
(EN)The invention uses the power of display selection methods to screen libraries of human immunoglobulin genes from nonhuman transgenic animals expressing human immunoglobulins. Such screening produces unlimited numbers of high affinity human antibodies to any target of interest.
(FR)L'invention met en application des procédés de sélection d'affichage servant à cribler des banques de gènes humains d'immunoglobuline provenant d'animaux transgéniques non humains exprimant des immunoglobulines humaines. Ce criblage permet d'obtenir des nombres illimités d'anticorps humains d'affinité élevée contre toute cible recherchée.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)