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Machine translation
1. (WO2001025401) A MYCOBACTERIUM TUBERCULOSIS CODING SEQUENCE FOR EXPRESSION OF HETEROLOGOUS PROTEINS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/025401    International Application No.:    PCT/US2000/027652
Publication Date: 12.04.2001 International Filing Date: 06.10.2000
Chapter 2 Demand Filed:    17.04.2001    
IPC:
C07K 14/35 (2006.01), C07K 14/47 (2006.01)
Applicants: CORIXA CORPORATION [US/US]; Suite 200, 1124 Columbia Street, Seattle, WA 98194 (US) (For All Designated States Except US).
SKEIKY, Yasir [CA/US]; (US) (For US Only).
GUDERIAN, Jeffrey [US/US]; (US) (For US Only)
Inventors: SKEIKY, Yasir; (US).
GUDERIAN, Jeffrey; (US)
Agent: CHOI, Kathleen, L.; Townsend and Townsend and Crew LLP, 8th Floor, Two Embarcadero Center, San Francisco, CA 94111-3834 (US)
Priority Data:
60/158,585 07.10.1999 US
Title (EN) A MYCOBACTERIUM TUBERCULOSIS CODING SEQUENCE FOR EXPRESSION OF HETEROLOGOUS PROTEINS
(FR) UTILISATION D'UNE SEQUENCE CODANTE DE MYCOBACTERIUM TUBERCULOSIS POUR FAVORISER UNE EXPRESSION STABLE ET DE FORT RENDEMENT DE PROTEINES HETEROLOGUES
Abstract: front page image
(EN)The present invention relates generally to nucleic acid and amino acid sequences of a fusion polypeptide comprising a Mycobacterium tuberculosis polypeptide, and a heterologous polypeptide of interest, expression vectors and host cells comprising such nucleic acids, and methods for producing such fusion polypeptides. In particular, the invention relates to materials and methods of using such M. tuberculosis sequence as a fusion partner to facilitate the stable and high yield expression of recombinant heterologous polypeptides of both eukaryotic and prokaryotic origin.
(FR)La présente invention concerne d'une façon générale des séquences d'acides nucléiques et d'acides aminés d'un polypeptide de fusion comprenant un polypeptide de mycobacterium tuberculosis. L'invention concerne également un polypeptide hétérologue particulier, des vecteurs d'expression et des cellules hôtes comprenant de tels acides nucléiques. L'invention concerne enfin des procédés de production de tels polypeptides de fusion. L'invention concerne plus particulièrement des matériaux et des procédés permettant d'utiliser une telle séquence de M. tuberculosis comme partenaires de fusion pour favoriser une expression stable et à bon rendement de polypeptides hétérologues de recombinaison, qu'ils soient d'origine eucaryote ou procaryote.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)