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Machine translation
1. (WO2001024763) COMPOSITIONS AND METHODS FOR TREATING CANCER USING IMMUNOCONJUGATES AND CHEMOTHERAPEUTIC AGENTS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/024763    International Application No.:    PCT/US2000/026800
Publication Date: 12.04.2001 International Filing Date: 29.09.2000
Chapter 2 Demand Filed:    27.04.2001    
IPC:
A61K 31/337 (2006.01), A61K 47/48 (2006.01)
Applicants: IMMUNOGEN, INC. [US/US]; 128 Sidney Street, Cambridge, MA 02139 (US) (For All Designated States Except US).
CHARI, Ravi, V., J. [US/US]; (US) (For US Only)
Inventors: CHARI, Ravi, V., J.; (US)
Agent: WIXON, Henry, N.; Hale and Dorr LLP, 1455 Pennsylvania Avenue, N.W., Washington, DC 20004 (US).
GRIEFF, Edward, D.; Hale and Dorr LLP, 1455 Pennsylvania Avenue, N.W., Washington, DC 20004 (US)
Priority Data:
60/157,051 01.10.1999 US
Title (EN) COMPOSITIONS AND METHODS FOR TREATING CANCER USING IMMUNOCONJUGATES AND CHEMOTHERAPEUTIC AGENTS
(FR) COMPOSITIONS ET METHODES DE TRAITEMENT DU CANCER UTILISANT DES IMMUNOCONJUGUES ET DES AGENTS CHIMIOTHERAPEUTIQUES
Abstract: front page image
(EN)The present invention is based on the discovery that the administration of at least one immunoconjugate and at least one chemotherapeutic agent provides an unexpectedly superior treatment for cancer. The present invention is directed to compositions comprising at least one immunoconjugate and at least one chemotherapeutic agent and to methods of treating cancer using at least one immunoconjugate and at least one chemotherapeutic agent. The present invention also provides methods of modulating the growth of selected cell populations, such as cancer cells, by administering a therapeutically effective amount of at least one chemotherapeutic agent and at least one immunoconjugate.
(FR)La présente invention est fondée sur la découverte selon laquelle l'administration d'au moins un immunoconjugué et d'au moins un agent chimiothérapeutique à un patient offrent une traitement nettement amélioré du cancer. La présente invention concerne des compositions comprenant au moins un immunoconjugué et au moins un agent chimiothérapeutiques et des méthodes de traitement du cancer utilisant au moins un immunoconjugué et au moins un agent chimiothérapeutique. La présente invention concerne également des méthodes permettant de moduler la croissance de certaines populations cellulaires, telles que les cellules cancéreuses, consistant à administrer une quantité thérapeutiquement efficace d'au moins un agent chimiothérapeutique et au moins un immunoconjugué à un patient.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)