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1. (WO2001023541) COMPOSITIONS AND METHODS FOR ALTERING GENE EXPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/023541    International Application No.:    PCT/US2000/027065
Publication Date: 05.04.2001 International Filing Date: 02.10.2000
Chapter 2 Demand Filed:    30.04.2001    
IPC:
A01K 67/027 (2006.01), C12N 9/10 (2006.01), C12N 15/63 (2006.01), C12N 15/67 (2006.01), C12N 15/85 (2006.01), C12N 15/90 (2006.01)
Applicants: ALEXION PHARMACEUTICALS, INC. [US/US]; Suite 360, 25 Science Park, New Haven, CT 06511 (US) (For All Designated States Except US).
FODOR, William, L. [US/US]; (US) (For US Only).
RAMSOONDAR, Jagdeece, J. [TT/US]; (US) (For US Only)
Inventors: FODOR, William, L.; (US).
RAMSOONDAR, Jagdeece, J.; (US)
Agent: WIXON, Henry, N.; Hale and Dorr LLP, 1455 Pennsylvania Avenue, N.W., Washington, DC 20004 (US)
Priority Data:
60/156,953 30.09.1999 US
Title (EN) COMPOSITIONS AND METHODS FOR ALTERING GENE EXPRESSION
(FR) COMPOSITIONS ET METHODES POUVANT MODIFIER L'EXPRESSION GENIQUE
Abstract: front page image
(EN)Disclosed are novel compositions and methods useful for modulating expression of a target gene in a cell by insertion of exogenous DNA sequence into the target gene. The compositions and methods of the invention are useful for generation of knockout animals including mammals.
(FR)L'invention concerne de nouvelles compositions et méthodes pouvant moduler l'expression d'un gène cible dans une cellule, par insertion d'une séquence d'ADN exogène dans le gène cible. Les compositions et méthodes de l'invention sont utiles pour la production d'animaux à gène inactivé, notamment de mammifères.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)