WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2001022937) COMPOSITIONS OF TOCOL-SOLUBLE THERAPEUTICS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/022937    International Application No.:    PCT/US2000/026467
Publication Date: 05.04.2001 International Filing Date: 27.09.2000
Chapter 2 Demand Filed:    25.04.2001    
IPC:
A61K 9/107 (2006.01), A61K 47/22 (2006.01)
Applicants: SONUS PHARMACEUTICALS, INC. [US/US]; 22026 20th Avenue, S.E., Suite 102, Bothell, WA 98021 (US) (For All Designated States Except US).
CONSTANTINIDES, Panayiotis [US/US]; (US).
LAMBERT, Karel [US/US]; (US).
TUSTIAN, Alexander [US/US]; (US).
NIENSTEDT, Andrew [US/US]; (US)
Inventors: CONSTANTINIDES, Panayiotis; (US).
LAMBERT, Karel; (US).
TUSTIAN, Alexander; (US).
NIENSTEDT, Andrew; (US)
Agent: RENZONI, George, E.; Christensen O'Connor Johnson Kindness PLLC, Suite 2800, 1420 Fifth Avenue, Seattle, WA 98101 (US)
Priority Data:
60/156,128 27.09.1999 US
Title (EN) COMPOSITIONS OF TOCOL-SOLUBLE THERAPEUTICS
(FR) COMPOSITIONS DE COMPOSES THERAPEUTIQUES SOLUBLES DANS LE TOCOL
Abstract: front page image
(EN)Tocol-based compositions of charged amphiphilic and water soluble pharmaceutically active compounds or their charged precursors are prepared by forming a tocol-soluble ion pair with an oppositely charged ion-pair forming compound capable of forming a tocol-soluble ion-pair with the active compound. Also disclosed are novel compounds tocopherolsuccinate-aspartate and tocopherolsuccinate-glutamate, which are useful as ion-pair forming compounds.
(FR)La présente invention concerne des compositions à base de tocol de composés chargés pharmaceutiquement actifs soluble dans l'eau et amphiphiles, ou de leurs précurseurs chargés. On prépare cette composition en formant une paire d'ions soluble dans le tocol avec un composé formant une paire d'ion chargés de façon opposée, qui peut former une paire d'ion soluble dans le tocol avec ce composé actif. Cette invention concerne aussi de nouveau composés tocophérolsuccinate-aspartate et tocophérolsuccinate-glutamate, qui conviennent comme composés formant une paire d'ions.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)