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1. WO2001013989 - TISSUE ELECTROPERFORATION FOR DRUG DELIVERY AND DIAGNOSTIC SAMPLING

Publication Number WO/2001/013989
Publication Date 01.03.2001
International Application No. PCT/US2000/023262
International Filing Date 24.08.2000
Chapter 2 Demand Filed 15.03.2001
IPC
A61N 1/32 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
CPC
A61B 5/14514
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
14507specially adapted for measuring characteristics of body fluids other than blood
1451for interstitial fluid
14514using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
A61N 1/306
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
20continuous direct currents
30Apparatus for iontophoresis, ; i.e. transfer of media in ionic state by an electromotoric force into the body; , or cataphoresis
303Constructional details
306Arrangements where at least part of the apparatus is introduced into the body
A61N 1/325
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
325for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
Applicants
  • JOHNSON AND JOHNSON CONSUMER COMPANIES, INC. [US]/[US]
Inventors
  • SUN, Ying
  • OAKESON, Ralph, W.
  • WISNIEWSKI, Stephen, J.
  • WANG, Jonas, C., T.
Agents
  • MCGOWAN, William, E.
Priority Data
60/150,63625.08.1999US
null23.08.2000US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) TISSUE ELECTROPERFORATION FOR DRUG DELIVERY AND DIAGNOSTIC SAMPLING
(FR) ELECTROPERFORATION DE TISSUS POUR L'ADMINISTRATION DE MEDICAMENTS ET LE PRELEVEMENT DIAGNOSTIQUE
Abstract
(EN) The present invention relates to a method and a device (500) for transporting a molecule through a mammalian barrier membrane (52) of at least one layer of cells comprising the steps of: ablating said membrane with an electric current from a treatment electrode; and utilizing a driving force to move said molecule through said perforated membrane.
(FR) La présente invention concerne un procédé et un dispositif (500) s'utilisant pour le transport d'une molécule à travers une membrane (52) barrière de mammifère constituée d'au moins une couche de cellules. Ce procédé comprend l'ablation de ladite membrane au moyen d'un courant électrique provenant d'une électrode de traitement; et l'utilisation d'une force d'entraînement pour déplacer ladite molécule à travers la membrane perforée.
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