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1. (WO2001005979) PROCESS FOR PRODUCING TARGET SUBSTANCE BY FERMENTATION METHOD
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/005979 International Application No.: PCT/JP2000/004774
Publication Date: 25.01.2001 International Filing Date: 14.07.2000
Chapter 2 Demand Filed: 02.02.2001
IPC:
C12N 9/12 (2006.01) ,C12N 15/67 (2006.01) ,C12N 15/74 (2006.01) ,C12P 13/08 (2006.01) ,C12P 13/14 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9
Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
10
Transferases (2.)
12
transferring phosphorus containing groups, e.g. kinases (2.7)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
67
General methods for enhancing the expression
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
N
MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15
Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09
Recombinant DNA-technology
63
Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
74
Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
13
Preparation of nitrogen-containing organic compounds
04
Alpha- or beta-amino acids
08
Lysine; Diaminopimelic acid; Threonine; Valine
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
P
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
13
Preparation of nitrogen-containing organic compounds
04
Alpha- or beta-amino acids
14
Glutamic acid; Glutamine
Applicants:
KIMURA, Eiichiro [JP/JP]; JP (UsOnly)
ITO, Hisao [JP/JP]; JP (UsOnly)
KURAHASHI, Osamu [JP/JP]; JP (UsOnly)
AJINOMOTO CO., INC. [JP/JP]; 15-1, Kyobashi 1-chome Chuo-ku, Tokyo 104-8315, JP (AllExceptUS)
Inventors:
KIMURA, Eiichiro; JP
ITO, Hisao; JP
KURAHASHI, Osamu; JP
Agent:
TOYAMA, Tsutomu ; Yokoyama Building, 6th Floor 4-10, Higashi Nihonbashi 3-chome Chuo-ku, Tokyo 103-0004, JP
Priority Data:
11/20526719.07.1999JP
Title (EN) PROCESS FOR PRODUCING TARGET SUBSTANCE BY FERMENTATION METHOD
(FR) METHODE D'ELABORATION D'UNE SUBSTANCE CIBLE PAR FERMENTATION
Abstract:
(EN) A process for producing a target substance by using a microorganism which comprises culturing the microorganism in a medium, producing and accumulating the target substance in the medium, and then collecting the target substance, wherein use is made of a microorganism capable of producing the target substance and having an enhanced RNA polymerase activity as the microorganism to thereby improve the productivity of the target substance.
(FR) L'invention concerne une méthode d'élaboration d'une substance cible, cette méthode consistant tout d'abord à prendre un micro-organisme pour le mettre en culture dans un milieu, puis à élaborer et à accumuler ladite substance cible dans ce milieu. Cette méthode consiste ensuite à recueillir la substance cible obtenue à l'aide d'un micro-organisme capable de produire cette substance cible et présentant une activité d'ARN polymérase améliorée, ce qui permet d'augmenter la productivité de ladite substance cible.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)