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Machine translation
1. (WO2001005433) DELIVERY AND RETENTION OF ACTIVITY AGENTS TO LYMPH NODES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/005433    International Application No.:    PCT/US2000/018135
Publication Date: 25.01.2001 International Filing Date: 30.06.2000
Chapter 2 Demand Filed:    09.02.2001    
IPC:
A61K 47/48 (2006.01), A61K 51/12 (2006.01)
Applicants: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM [US/US]; 201 W. 7th Street, Austin, TX 78701 (US) (For All Designated States Except US).
GOINS, Beth, A. [US/US]; (US) (For US Only).
PHILLIPS, William, T. [US/US]; (US) (For US Only)
Inventors: GOINS, Beth, A.; (US).
PHILLIPS, William, T.; (US)
Agent: CATHERINE Alain et al; Cabinet HARLE & PHELIP, 7 rue de Madrid, 75008 Paris (FR)
Priority Data:
60/143,742 14.07.1999 US
Title (EN) DELIVERY AND RETENTION OF ACTIVITY AGENTS TO LYMPH NODES
(FR) METHODES ET COMPOSITIONS POUR LA LIBERATION ET LA RETENTION D'AGENTS ACTIFS DANS DES GANGLIONS LYMPHATIQUES
Abstract: front page image
(EN)The present invention is directed to delivery and retention of active agents to targeted lymph nodes in a mammal using a ligand/anti-ligand pair. More particularly, the invention involves methods, compositions, and kits for delivery and retention of active agents to targeted lymph nodes using compositions comprising a ligand-colloid moiety and compositions comprising an anti-ligand. Active agents may be associated with one or more of the colloid, ligand, or anti-ligand. Conjugation of the ligand and anti-ligand after administration permits retention of aggregated colloid complex in targeted lymph nodes.
(FR)L'invention concerne la libération et la rétention d'agents actifs dans des ganglions lymphatiques cibles chez un mammifère, au moyen d'une paire de ligand/anti-ligand. L'invention porte, plus particulièrement, sur des méthodes, des compositions et des kits pour la libération et la rétention d'agents actifs dans des ganglions lymphatiques cibles, au moyen de compositions comprenant un fragment de ligand-colloïde et de compositions comprenant un anti-ligand. Les agents actifs peuvent être associés à au moins un parmi le colloïde, le ligand ou l'anti-ligand. La conjugaison du ligand et de l'anti-ligand après l'administration permet la rétention du complexe colloïdale agrégé dans les ganglions lymphatiques cibles.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)