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1. (WO2001005399) ANTI-ISCHEMIC AGENT
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/005399 International Application No.: PCT/RU2000/000222
Publication Date: 25.01.2001 International Filing Date: 08.06.2000
Chapter 2 Demand Filed: 20.11.2000
IPC:
A61K 31/4015 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
40
having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
4015
having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
Applicants: TJURENKOV, Ivan Nikolaevich[RU/RU]; RU (UsOnly)
BERESTOVITSKAYA, Valentina Mikhailovna[RU/RU]; RU (UsOnly)
ZOBACHEVA, Maya Mikhailovna[RU/RU]; RU (UsOnly)
VASILEVA, Olga Sergeevna[RU/RU]; RU (UsOnly)
USIK, Nina Vladimirovna[RU/RU]; RU (UsOnly)
NOVIKOV, Boris Mikhailovich[RU/RU]; RU (UsOnly)
ZAKRYTOE AKTSIONERNOE OBSCHESTVO 'ASGL-ISSLEDOVATELSKIE LABORATORII'[RU/RU]; Kronverxky pr., 71/46, lit. A St.Petersburg, 197198, RU (AllExceptUS)
ROSSYSKY GOSUDARSTVENNY PEDAGOGICHESKY UNIVERSITET IM. A.I.GERTSENA[RU/RU]; nab . reki Moiki, 48 St.Petersburg, 191186, RU (AllExceptUS)
Inventors: TJURENKOV, Ivan Nikolaevich; RU
BERESTOVITSKAYA, Valentina Mikhailovna; RU
ZOBACHEVA, Maya Mikhailovna; RU
VASILEVA, Olga Sergeevna; RU
USIK, Nina Vladimirovna; RU
NOVIKOV, Boris Mikhailovich; RU
Common
Representative:
ZAKRYTOE AKTSIONERNOE OBSCHESTVO 'ASGL-ISSLEDOVATELSKIE LABORATORII'; Kronverksky pr., 71/46, lit. A St.Petersburg, 197198, RU
Priority Data:
19990087821.07.1999EA
Title (EN) ANTI-ISCHEMIC AGENT
(FR) AGENT ANTI-ISCHEMIQUE
Abstract:
(EN) The present invention pertains to the field medicine and to the pharmaceutical industry and essentially relates to agents having an influence on the cardio-vascular system. This invention essentially relates to the use of a 4-carbamoylmethyl-4-phenyl-2-pyrrolidone as an anti-ischemic agent whose hypotensive and cognition-enhancing activity has been previously described. It has been shown that the anti-ischemic activity was higher than that of obsidan. However, unlike the latter, the agent of the present invention has no negative inotropic activity.
(FR) Cette invention se rapporte au domaine de la médecine et de l'industrie pharmaceutique, et concerne des agents qui ont une action sur le système cardio-vasculaire. Cette invention concerne notamment l'utilisation de 4-carbamoylméthyl-4-phényl-2-pyrrolidone en qualité d'agent anti-ischémique dont on a précédemment décrit l'activité hypotensive et nootrope. Il a été prouvé que l'activité anti-ischémique de cet agent était supérieure à celle de l'obsidane. Toutefois, à la différence de ce dernier, l'agent décrit dans cette invention n'a pas d'action inotrope négative.
Designated States: JP, US
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
Publication Language: Russian (RU)
Filing Language: Russian (RU)