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Machine translation
1. (WO2001005389) N-SULFONYLAMINIACID DERIVATIVES AS INHIBITORS OF METALLOPRTEINASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/005389    International Application No.:    PCT/US2000/016323
Publication Date: 25.01.2001 International Filing Date: 12.07.2000
Chapter 2 Demand Filed:    30.01.2001    
IPC:
A61K 31/635 (2006.01), C07C 311/46 (2006.01)
Applicants: G.D. SEARLE & CO. [US/US]; Corporate Patent Department, P.O. Box 5110, Chicago, IL 60680-5110 (US) (For All Designated States Except US).
STALLINGS, William, C. [US/US]; (US) (For US Only).
SHIEH, Huey, S. [US/US]; (US) (For US Only).
HOWARD, Susan, C. [US/US]; (US) (For US Only).
DE CRECENZO, Gary, A. [US/US]; (US) (For US Only).
MC DONALD, Joseph, J. [US/US]; (US) (For US Only)
Inventors: STALLINGS, William, C.; (US).
SHIEH, Huey, S.; (US).
HOWARD, Susan, C.; (US).
DE CRECENZO, Gary, A.; (US).
MC DONALD, Joseph, J.; (US)
Agent: WARNER, James, M.; G.D. Searle & Co., Corporate Patent Department, P.O. Box 5110, Chicago, IL 60680-5110 (US).
ALBRECHT, Thomas; Kraus & Weisert, Thomas-Wimmer-Ring 15, D-80539 Munich (DE)
Priority Data:
60/144,133 16.07.1999 US
Title (EN) N-SULFONYLAMINIACID DERIVATIVES AS INHIBITORS OF METALLOPRTEINASE
(FR) METHODE DE CHANGEMENT DE LA CONFORMATION D'UNE METALLOPROTEINASE MATRICIELLE
Abstract: front page image
(EN)The present invention provides a matrix metalloproteinase inhibiting compound having structure (VIII) or a salt, an enantiomer, a diastereomer, a racemate, or a tautomer thereof. In other embodiments, the present invention provides a method of changing the conformation of a matrix metalloproteinase, a method of inhibiting a matrix metalloproteinase, and a method of treating osteoarthritis.
(FR)La présente invention concerne un composé inhibant une métalloprotéinase matricielle ayant la structure (VIII) ou un sel, un énantiomère, un diastéréomère, un racémate ou un tautomère de celui-ci. Dans d'autres modes de réalisation, la présente invention concerne une méthode de changement de la conformation d'une métalloprotéinase matricielle, une méthode d'inhibition d'une métalloprotéinase matricielle ainsi qu'une méthode de traitement de l'ostéoarthrite.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, BZ, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)