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1. (WO2001005382) SYNERGISTIC COMPOSITION COMPRISING DAUNORUBICIN DERIVATIVES AND ANTIMETABOLITE COMPOUNDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/005382    International Application No.:    PCT/EP2000/006545
Publication Date: 25.01.2001 International Filing Date: 10.07.2000
Chapter 2 Demand Filed:    13.02.2001    
IPC:
A61K 31/70 (2006.01)
Applicants: PHARMACIA & UPJOHN SPA [IT/IT]; Via Robert Koch, 1.2 I-20152 Milan (IT) (For All Designated States Except US).
GERONI, Maria, Cristina [IT/IT]; (IT) (For US Only).
RIPAMONTI, Marina [IT/IT]; (IT) (For US Only).
CARUSO, Michele [IT/IT]; (IT) (For US Only).
SUARATO, Antonino [IT/IT]; (IT) (For US Only)
Inventors: GERONI, Maria, Cristina; (IT).
RIPAMONTI, Marina; (IT).
CARUSO, Michele; (IT).
SUARATO, Antonino; (IT)
Priority Data:
9916882.5 19.07.1999 GB
Title (EN) SYNERGISTIC COMPOSITION COMPRISING DAUNORUBICIN DERIVATIVES AND ANTIMETABOLITE COMPOUNDS
(FR) COMPOSITION A SYNERGIE COMPORTANT DES DERIVES DAUNORUBICINES ET DES COMPOSES ANTIMETABOLITES
Abstract: front page image
(EN)The combined use of 4-demethoxy-3'-deamino-3'-aziridinyl-4'-methansulfonyl daunorubicin or 4-demethoxy-N,N-bis(2-chloroethyl)-4'-methansulfonyl daunorubicin and an antimetabolite compound in the treatment of tumors, especially in the treatment or prevention of metastasis or in the treatment of tumors by the inhibition of angiogenesis.
(FR)La présente invention concerne l'administration combinée, d'une part la 4-déméthoxy-3'-déamino-3'-aziridinyl-4'-méthansulfonyl daunorubicine ou la 4-déméthoxy-N,N-bis(2-chloroéthyl)-4'-méthansulfonyl daunorubicine, et d'autre part un composé antimétabolite pour le traitement ou la prévention de la métastase ou pour le traitement de tumeurs par inhibition de l'angiogenèse.
Designated States: AE, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)