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1. (WO2001005369) TREATMENT AND COMPOSITION FOR ACHIEVING SKIN ANTI-AGING BENEFITS BY CORNEUM PROTEASE ACTIVATION
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2001/005369 International Application No.: PCT/US2000/019477
Publication Date: 25.01.2001 International Filing Date: 17.07.2000
Chapter 2 Demand Filed: 20.02.2001
IPC:
A61K 8/40 (2006.01) ,A61Q 19/08 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8
Cosmetics or similar toilet preparations
18
characterised by the composition
30
containing organic compounds
40
containing nitrogen
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
Q
SPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19
Preparations for care of the skin
08
Anti-ageing preparations
Applicants: SCHILTZ, John, R.[US/US]; US (UsOnly)
MARY KAY, INC.[US/US]; 16251 Dallas Parkway Dallas, TX 75248, US (AllExceptUS)
Inventors: SCHILTZ, John, R.; US
Agent: WILSON, Mark, B.; Fulbright & Jaworski, L.L.P. Suite 2400 600 Congress Avenue Austin, TX 78701, US
CATHERINE, Alain; Harle & Phélip 7 rue de Madrid F-75008 Paris, FR
Priority Data:
09/357,28820.07.1999US
Title (EN) TREATMENT AND COMPOSITION FOR ACHIEVING SKIN ANTI-AGING BENEFITS BY CORNEUM PROTEASE ACTIVATION
(FR) TRAITEMENT ET COMPOSITIONS PRODUISANT DES EFFETS ANTI-VIEILLISSEMENT PAR ACTIVATION DES PROTEASES DE LA COUCHE CORNEE
Abstract:
(EN) Novel methods and compositions for treating aged and environmentally damaged skin are disclosed which provide improvements in the skin's visual appearance, function and clinical/biophysical properties by activating at least one proteolytic enzyme in the skin's stratum corneum. The disclosed treatment methods involve topical application of a novel cosmetic composition containing a combination of a cationic surfactant such as N,N,-dimethyldodecyl amine oxide (DMDAO), an anionic surfactant such as sodium dodecyl sulfate (SDS), or monoalkyl phosphate (MAP) and a chelating agent such as ethylene diamine tetraacetate (EDTA) to stimulate a chronic increase in the replacement rate of the skin's stratum corneum by means of corneum protease activation. This chronic, low level stimulation is effective to induce repair and replacement of the stratum corneum, epidermis, and dermis of the skin and improvements in the appearance, function, and anti-aging properties of the skin.
(FR) L'invention concerne de nouvelles méthodes et de nouvelles compositions pour le traitement de la peau vieillie et abîmée par l'environnement. Ces procédés et compositions améliorent l'aspect, la fonction, et les caractéristiques cliniques/biophysiques de la peau par l'activation d'au moins un enzyme protéolytique dans la couche cornée de la peau. Le traitement comprend l'application topique d'une nouvelle composition cosmétique combinant un tensioactif cationique tel que l'oxyde de N,N,-diméthyldodécyl amine (DMDAO), un tensioactif anionique tel que le dodécyl sulfate de sodium (SDS), ou le phosphate monoalkylique (MAP) et un chélateur tel que l'éthylène diamine tétraacétate (EDTA), afin de susciter une augmentation durable de la vitesse de remplacement de la couche cornée de l'épiderme au moyen d'une activation des protéases de la couche cornée. Cette stimulation durable de faible intensité a pour effet d'induire la réparation et le remplacement de la couche cornée, de l'épiderme et du derme de la peau, ainsi que des améliorations de l'aspect, de la fonction et des capacités anti-vieillissement de la peau.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW
African Regional Intellectual Property Organization (ARIPO) (GH, GM, KE, LS, MW, MZ, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)