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Machine translation
1. (WO2001004348) METHODS TO IDENTIFY INHIBITORS OF F1/F0 ATPASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2001/004348    International Application No.:    PCT/US2000/009252
Publication Date: 18.01.2001 International Filing Date: 06.04.2000
Chapter 2 Demand Filed:    07.02.2001    
IPC:
C12Q 1/18 (2006.01), C12Q 1/42 (2006.01)
Applicants: XOMA TECHNOLOGY LTD. [--/--]; c/o Xoma (US) LLC, 2910 Seventh Street, Berkeley, CA 94710 (US) (For All Designated States Except US).
LITTLE, Roger, G. [US/US]; (US) (For US Only).
ABRAHAMSON, Susan [US/US]; (US) (For US Only)
Inventors: LITTLE, Roger, G.; (US).
ABRAHAMSON, Susan; (US)
Agent: RIN-LAURES, Li-Hsien; Marshall, O'Toole, Gerstein, Murray & Borun, 6300 Sears Tower, 233 South Wacker Drive, Chicago, IL 60606-6402 (US)
Priority Data:
60/143,372 12.07.1999 US
Title (EN) METHODS TO IDENTIFY INHIBITORS OF F1/F0 ATPASE
(FR) METHODES D'IDENTIFICATION D'INHIBITEURS D'ATPASE F1/F0
Abstract: front page image
(EN)Novel methods of identifying antifungal agents and therapeutic uses are provided comprising the steps of: (a) selecting a test compound that produces a decrease in the activity of a fungal mitochondrial F1/F0 ATP synthase; and (b) detecting inhibition of growth of fungal cells in the presence of the selected test compound from step (a).
(FR)L'invention concerne de nouvelles méthodes d'identification d'agents antifongiques et des utilisations thérapeutiques. Lesdites méthodes consistent à (a) sélectionner un composé test qui produit une diminution de l'activité d'une synthèse mitochondriale fongique d'ATP F1/F0, et (b) détecter l'inhibition de la croissance de cellules fongiques en présence du composé test sélectionné lors de la première étape (a).
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BY, CA, CH, CN, CR, CU, CZ, DE, DK, DM, DZ, EE, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, NO, NZ, PL, PT, RO, RU, SD, SE, SG, SI, SK, SL, TJ, TM, TR, TT, TZ, UA, UG, US, UZ, VN, YU, ZA, ZW.
African Regional Intellectual Property Organization (GH, GM, KE, LS, MW, SD, SL, SZ, TZ, UG, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, CH, CY, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)